PubMed Health⌕ Search

Biomedical subjects

J Roubicek

Publications and source records attributed to J Roubicek.

16 recordsLinked to original sources
PubMed1977

The electroencephalogram in the middle-aged and the elderly.

A survey was made of the electroencephalographic (EEG) changes during the human lifespan. It was found that the EEG changes during childhood and adolescent maturation continue even between the ages of 30 and 60 years. There is a decrease in the abundance of alpha activity, with a reduction in the fast part and a relative increase in the slow part of the alpha band. In the span of life between 60 and 90, there is an increase of slow waves with a progressive slowing during the aging process and a shift in the dominant frequency from 9 cps to 7 cps. Computerization of results in the beta band (above 13 cps) enables differentiation of the waves of the lower part (13-25 cps) from those of the upper part (above 25-30 cps). The lower part of the beta band decreases parallel to the alpha activity but the upper part of the beta band increases in amount during the aging process. The meaning of the divergent behavior of these sub-groups of beta activity in the aged is discussed. The EEG seems to be an important factor in the study of aged persons.

Adolescent↗
PubMed1977

EEG profile and behavioral changes after a single dose of clozapine in normals and schizophrenics.

Clozapine, a powerful neuroleptic with unique clinical efficacy (and without parkinsonic side effects), has been shown to have an unusual EEG profile. The EEG changes after clozapine, especially when instrumentally quantified, demonstrated the predictive value of EEG. The similarities of the EEG profile of clozapine with the profile of thymoleptic compounds indicated its possible thymoleptic effect. This later proved to be the case with therapeutic studies in depression. The EEG profile of clozapine in volunteers is similar to the EEG profile in schizophrenics (with appropriately higher doses). Instrumental quantification was performed with spectral and iterative interval analysis to show the advantages of each method and also the complementary value of both of them.

Adult↗
PubMed1975

Franz Kafka.

The hereditary and environmental influences on the genius of Kafka's personality are discussed. His exterior, somatic constitution is represented by photos taken during his lifetime as well as some posthumous, imaginary portraits and sculptures by various, mostly Prague, artists. The concept of the artist's psychic formation - his mental makeup - is documented from his diary, dreams, letters, literary work and reports by his friends. The whole proves his introversion, ambivalence, hypersensitivity, obstinancy, anxieties, behavioral anomalies, a life rich in fantasies and his underestimation of his own literary work. (He speaks about it as an idiosyncrasy, wishing it to be burned after his death.) Some little-known drawings by Kafka complement the picture of his talents and creativity. The psychological and psychopathological roots of his extraordinary position in the cultural awareness of his epoch are discussed.

Czechoslovakia↗