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Biomedical subjects

J Ruiz Tramazaygues

Publications and source records attributed to J Ruiz Tramazaygues.

4 recordsLinked to original sources

[HYPNOS and Revista Española de Anestesiología y Reanimación, history of a coexistence relationship].

The year 2003 will mark the fiftieth anniversary of the publication of Revista Española de Anestesiología y Reanimación (Spanish Journal of Anesthesiology and Postoperative Recovery). For that reason, it is appropriate to explore some of the details of the journal's early history. In 1954 and 1955 two official journals of anesthesiology co-existed in Spain: Revista Española de Anestesiología, which was the official organ of the Spanish Society of Anesthesiology and Postoperative Recovery, and Hypnos, which was the bulletin of the Association of Anesthesia of the Academy of Medical Sciences of Barcelona. The two publications merged in 1956 as Revista Española de Anestesiología, thereby forming the journal whose name eventually became Revista Española de Anestesiología y Reanimación.

Anesthesia↗

[Severe perioperative hypotension after nephrectomy with adrenalectomy].

A 70-year-old obese, hypertensive woman taking angiotensin converting enzyme (ACE) inhibitors and chlorthalidone but with no history of corticosteroid treatment or hypothalamus-hypophyseal-adrenal disease, underwent nephrectomy and adrenalectomy under combined general and epidural anesthesia. Severe hypotension with oliguria developed during surgery and persisted during postoperative recovery, with anuria, metabolic acidosis, hyponatremia and hyperpotassemia. Although the symptoms were initially attributed to prior treatment with ACE inhibitors and diuretics together with combined anesthesia, the patient's lack of response to crystalloid, colloid and inotropic catecholamine therapy in the context of anuria, metabolic acidosis, hyponatremia and hyperpotassemia led us to consider a diagnosis of Addisonian crisis. Blood samples were taken to determine adrenocorticotropic hormone levels, and hydrocortisone treatment was started. The patient responded to treatment and cortisol levels fell, confirming the diagnosis of adrenal insufficiency. Compensatory endrocrine secretion of cortisol by the contralateral adrenal gland has been observed in patients undergoing nephrectomy and adrenalectomy for excision of a hypernephroma, and replacement therapy is therefore not recommended. Perioperative Addisonian crises have also been described in patients suffering great surgical stress, and severe hypotension has been observed in patients on long-term treatment with ACE inhibitors after induction of general anesthesia and after epidural anesthesia with local anesthetics. The combination of these factors made rapid diagnosis and start of appropriate therapy difficult.

Addison Disease↗