Biomedical subjects
Publications and source records attributed to J S Edirisinghe.
A case of an adult filarial worm (Wuchereria bancrofti) associated with a benign ovarian tumour and a cyst is presented. Possible reasons for the findings of a well preserved part of the worm and a foreign body granuloma in the lymphatic subendothelium are discussed.
A case of myiasis due to Cardylobia anthropophaga (Blanchard) (Diptera: Calliphoridae), the 'Tumbu fly', is reported for the first time in Sri Lanka, in a 10 month old infant. The infection was acquired in Zimbabwe. The child had appeared 'unwell' for nearly a week before the detection of the skin lesions. The main clinical features were irritability, restlessness and the appearance of three small lumps on the scalp behind the right ear. Identification of the fly larva and the management of myiasis are discussed.
The efficacy of a single large dose of mebendazole was compared with the three-day multiple dose in mass treatment. The subjects were selected from among plantation workers of a tea estate in Kandy. The multiple dose regime showed consistently better egg reduction rates and cure rates when compared to the single large dose in subjects harbouring one or more soil-transmitted helminths.
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Explore the source record for details and available documents.
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The inter-relationship of malnutrition and infections is generally accepted as being synergistic, one promoting the other. Nevertheless, numerous published reports are available which highlight the contrary, that is, antagonism of poor nutrition to infections. This presentation is a review of such publications with emphasis on malaria and malnutrition in the tropics. The data presented suggest that the effect of poor diets on human malaria is related to the level of protein and energy intake, which in turn have important bearings not only on clinical nutrition but also on nutrition policy and planning, particularly in famine and famine relief. The data highlight the necessity for the integration of nutritional programmes and anti-malarial activities in areas where famine and malaria co-exist.
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