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Biomedical subjects

J S Gillick

Publications and source records attributed to J S Gillick.

8 recordsLinked to original sources
PubMed1977

The metastatic spread of bronchogenic carcinoma in relation to the interval between resection and death.

Information from autopsy was obtained for 125 men who had had lung cancer resected. Metastases were most common among men whose carcinoma was undifferentiated, while the prevalence among those with squamous cell carcinoma and those with adenocarcinoma was about the same. Among men whose cancers were of the latter two types, extrathoracic metastases were more common among men with adenocarcinoma than among those with squamous cell carcinoma. In 44 cases with postoperative death, metastases were found in 36 percent (16 cases). With the passage of time, the incidence of metastases rose rapidly to 85 percent (17/20) 6 to 11 months after resection. These data support the concept that metastatic disease is often present at the time of diagnosis.

Adenocarcinoma↗
PubMed1976

The inflation-catheter technique of ventilation during laryngoscopy.

Over the past three years the inflation-catheter technique (ICT) of controlled ventilation during general anaesthesia has proved a safe and useful method for use with laryngoscopy and other trans-oral endoscopies (most notably flexible fiberoptic bronchoscopy). The ICT allows full control of the patient's airway for the anaesthetist and exceptionally good exposure for the surgeon. In this technique ventilation of the patient is accomplished by intermittent high flow (10 ml/kg/sec) inflation of the lungs through a small (2 to 6 mm diameter) plastic orotracheal catheter. The inflation-catheter is stiffened by fixation of an intralumenal wire. Exhalation is passive around the catheter through the open airway. The Inflation Catheter Technique is readily adaptable for patients ranging from large adults to small babies by variation of catheter sizes. It can be used safely with nitrous oxide-oxygen as the ventilating gas(i.e., Bird N2O/O2 Blender) since air entrainment is not a feature. It is also readily adaptable for use with mechanical ventilation (i.e., Wolf Injectomat).

Adult↗
PubMedDate not supplied

Spontaneous positive end-expiratory pressure (sPEEP).

Spontaneous positive end-expiratory pressure (sPEEP) is a simple, low-cost method of providing low to moderate levels of PEEP as an alternative to continuous positive airway pressure (CPAP), whether used alone or with continuous positive pressure ventilation (CPPV) in intermittent mandatory ventilation (IMV). The therapeutic effects of sPEEP therapy are demonstrated in 7 adult respiratory distress syndrome patients. All patients, initially hypoxemic on a high F1O2, had an acceptable PaO2 (with F1O2 less than or equal to 0.4) within 12 hours of initiation of sPEEP therapy. sPEEP, unlike CPAP and CPPV, does not maintain a continuous positive intrathoracic pressure during inspiration. Therefore, the patient probably does not receive as great a negative effect on venous return and cardiac output. By use of the sPEEP apparatus, the patient receives the therapeutic effect of PEEP.

Adult↗