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Biomedical subjects

J S Griffith

Publications and source records attributed to J S Griffith.

10 recordsLinked to original sources
PubMed1988

Apomorphine-induced vomiting in rainbow trout (Salmo gairdneri).

1. The LD50 for a 7-day period following intraperitoneal injection of apomorphine-HCl was calculated to be 158 mg/kg in rainbow trout. 2. Intraperitoneal injection of apomorphine at doses of 60 mg/kg or greater caused vomiting of plastic balls which had been placed in the stomachs of rainbow trout. 3. Apomorphine-induced effects included vomiting, vomiting behavior, toxicity, increased respiration, impaired motor control and equilibrium, and increased aggression. 4. The vomiting control mechanism of trout may be similar to that described in mammals.

Aggression↗
PubMed1966

An analysis of spontaneous impulse activity of units in the striate cortex of unrestrained cats.

1. Recordings were made from sixty-five cells in the visual cortex of unanaesthetized, dark-adapted cats and transferred automatically to computer input paper tape.2. The activity of each cell was measured as a function of time (the running mean). The unit of time used was inversely proportional to the mean firing rate, in order to give comparable results for different cells.3. For sixty-nine sections of discharge from fifty-two cells, the length of time recorded was sufficient to test for the long-term stability of the running mean. In twenty-six sections, various kinds of trend and long-term irregularity were found.4. The interspike interval histogram was computed for the forty-one sections (from thirty-one cells) in which there were more than 2000 discharges. Only eight histograms approximated closely to the exponential form. A test was also made of the distribution of the longer intervals alone and in twenty-five sections they did not deviate significantly from the exponential form.5. There was no significant correlation between the behaviour of the longer interspike intervals and the long-term stability or otherwise of the running mean.

Adaptation, Physiological↗