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Biomedical subjects

J S Howland

Publications and source records attributed to J S Howland.

4 recordsLinked to original sources

Does patient education cause side effects? A controlled trial.

Ninety-eight adults treated with erythromycin for a variety of illnesses were randomized to two groups: the informed group received patient education about drug side effects, and the uninformed group were given no such information. Overall, 10% of the uniformed and 8% of the informed group felt the erythromycin bothered them in some way. There were no significant differences in the occurrence of various individual side effects. Compliance with therapy and the results of treatment were the same for both groups. In this study, informing patients about side effects of therapy did not have any detectable adverse effects.

Adult↗

Cardiomyopathy associated with tricyclic antidepressants.

Nine other cases of cardiomyopathy in patients taking tricyclic antidepressants have been reported. The patient we have described had been taking tricyclic antidepressants for years before cardiomyopathy developed. While a cause-and-effect relationship between tricyclic antidepressants and cardiomyopathy cannot be proven, physicians should keep in mind the association and discontinue the medication if cardiomyopathy develops. Further, tricyclic antidepressants should be used with great caution in patients with cardiomyopathy because of possible risk of ventricular fibrillation.

Animals↗

Long-term survival of 224 patients with myocardial infarction treated in a community hospital.

In a retrospective, five-year follow-up study of 224 patients treated for acute myocardial infarction in a community hospital, there was an 82 percent in-hospital survival rate and an overall 57 percent five-year survival rate. Corrected for expected mortality, the five-year survival rate was 68 percent. Patients who had had a previous infarction had a lower five-year survival rate, 40 percent. Survival decreased significantly with age, but was not affected by hypertension, diabetes, smoking, sex, or obesity (when corrected for age differences). Women and nonsmokers who had myocardial infarctions could expect to have longer lifespans than men and smokers because they were older at the time of their infarction. At the time of their infarction, women averaged 68 years of age, men 60 years. Nonsmokers averaged 67 years, smokers 55 years.

Adult↗

The use of hypnosis in the treatment of a case of multiple personality.

The literature regarding the use of hypnosis in the therapy of multiple personality is reviewed. Cautions of other authors are noted which intend to protect the patient from further "splitting" of the personalities involved. A case of a 25-year-old woman is described in which, several months after leaving therapy abruptly, a second personality appeared and prompted her re-entry into treatment. Hypnosis was employed several weeks after restarting therapy on four separate occasions. Therapeutic outcome was favorable with coalescence of the personality into a new whole. A rationale for the use of hypnosis in this case is presented.

Adult↗