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Biomedical subjects

J S Long

Publications and source records attributed to J S Long.

5 recordsLinked to original sources

Evaluation of enzyme immunoassay performance characteristics--phencyclidine example.

Four reagent formulations (three provided by a manufacturer; one prepared in-house by mixing equal volumes of two commercial reagents) are used for the assay of phencyclidine (PCP) in urine samples. Performance characteristics evaluated included assay precision and sensitivity at and near the assay cutoff concentration. Data resulting from the reagent prepared in-house are better than those using then commercially available formulations, and are comparable with those obtained using the recently available new commercial formulation.

Enzyme Multiplied Immunoassay Technique

Renin release from the ischaemic kidney.

1. We have confirmed that spinal section, and also pithing, inhibits the pressor response associated with the release of renin that follows re-establishment of circulation to the ischaemic rat kidney. Brain transections at bulbar and midthalamic levels did not modify the blood pressure elevation.2. Several pharmacological antagonists of the sympathetic nervous system did not modify the blood pressure response. These observations are not consistent with the view that a neural element is necessary for renin release.3. Constant flow perfusion of the ischaemic kidney in the intact and spinal sectioned rat was performed to evaluate haemodynamic factors involved in renin release. The pressor response was present in spinal sectioned animals under these conditions.4. These results suggest that the nervous system is necessary to maintain adequate blood flow for renin ;washout' into the systemic circulation rather than to release renin from juxtaglomerular cells.

Animals

Shoulder arthroscopy.

Shoulder arthroscopy is a well-established surgical procedure. Arthroscopy is used to confirm clinical diagnosis, establish details of shoulder pathology, perform surgical procedures relative to pathology, and plan for subsequent management. Anatomy and pathology of the shoulder, holmium laser applications, advantages and complications, and rehabilitation are discussed in this article.

Arthroscopes