PubMed Health⌕ Search

Biomedical subjects

J S Masterson

Publications and source records attributed to J S Masterson.

6 recordsLinked to original sources

Dicentric Y chromosome and mixed dysgenesis.

We report 4 cases of mixed gonadal dysgenesis with a karyotype containing a dicentric Y chromosome. All cases were mosaic with 45X and 46X, dic(Y) cell lines. Of the patients 1 had ambiguous genitalia and some features of Turner's syndrome, 2 had classical features of Turner's syndrome with normal female external genitalia and 1 had no features of Turner's syndrome but he presented with penoscrotal hypospadias, inguinal hernia and cryptorchidism. Female gender assignment and early total gonadectomy should be considered when a dicentric Y chromosome is present in cases of mixed gonadal dysgenesis.

Child, Preschool↗

Neonatal gonadal stromal tumor of the testis: limitations of tumor markers.

We report case 10 of a gonadal stromal tumor of the testis in a neonate. This tumor may occur in the testis or ovary, and is defined as a tumor of any of the specialized supporting structures of the male or female gonad. All neonatal tumors reported to date have been benign. The serum alpha-fetoprotein level, although elevated for adults, was within the normal range for an infant.

Humans↗

The development of microsurgical techniques in experimental and clinical repair of urethrocutaneous fistulas.

We reviewed 60 urethral fistulas in 50 patients seen between 1974 and 1979. After the results of this study were assessed technical aspects of the repair were incriminated to account for the 40 per cent failure rate for first-time closure of urethral fistulas in our area. To study this problem an animal model was created in the laboratory. A comparison was made between classically repaired fistulas and those repaired with microsurgical equipment and techniques. In the group repaired by a classical macrosurgical technique only 20 per cent of the repairs were successful, while 90 per cent of the repairs under the microscope succeeded. Techniques and material, as well as histology involved, are presented in detail. Some of the causes of fistula repair breakdown clarified in this study include tissue trauma "para fistula" fistulas due to needle trauma and nonrecognition of multiple small additional fistulas. Details of 25 fistulas in 19 patients in whom closures were done with microsurgical techniques are presented. Success rate for primary closure was 88 per cent.

Animals↗

Vesicopsoas hitch: a versatile procedure.

The vesicoposoas hitch is an ideal operation for the management of lower ureteral injury and disease requiring replacement of varying lengths of ureter. It is safe and easy to perform, complications are minimal and the success rate is high. In combination with the Boari flap and downward mobilization of the kidney, up to 70% of the ureter may be replaced by this technique. The authors describe their experience between 1970 and 1980 with 52 patients treated by the vesicopsoas hitch, with and without the Boari flap.

Adult↗

Treatment of pneumatosis cystoides intestinalis with hyperbaric oxygen.

The use of hyperbaric oxygen for the treatment of pneumatosis cystoides intestinalis is reported. The pathophysiology, etiology and previous treatment reports are discussed, as are the advantages of hyperbaric oxygen therapy over normobaric oxygen therapy or surgery. The use of hyperbaric oxygen appears to represent a significant advance in the treatment of pneumatosis cystoides intestinalis.

Adult↗

Universal cardiac valve holder.

A valve holder has been designed to facilitate the insertion of porcine cardiac valves. This holder allows a return to the operative technique established with the earlier generation of mechanical cardiac valves.

Animals↗