PubMed HealthSearch

Biomedical subjects

J S Smeltzer

Publications and source records attributed to J S Smeltzer.

11 recordsLinked to original sources

Relationship of measured external tocodynamometry with measured internal uterine activity.

The use of home uterine activity monitoring for patients at high risk for preterm labor and delivery has become common in clinical perinatology. The ability of the monitoring devices to detect accurately uterine contractions in early pregnancy has not previously been reported. Ten women in labor between 20 and 35 weeks' gestation underwent simultaneous monitoring of uterine activity with a guard-ring tocodynamometer and an intrauterine pressure monitor. When compared with internal monitoring, the external monitor detected 90.8% of uterine contractions with a specificity for uterine quiescence of 98.1%. The predictive value of external monitoring was 97.3% for detecting uterine contractions and 93.6% for recording the absence of uterine contractions. The contractions detected externally were similar in duration: mean 63.7 +/- 23.0 seconds for internal monitoring and 62.2 +/- 22.6 seconds for external monitoring (p greater than 0.05). The intensity of contractions detected externally was less than internally measured contractions, mean difference, 19.7 +/- 15.9 mmHg (p less than 0.001). External tocodynamometry using this guarding tocodynamometer reliably distinguishes between uterine contractions and uterine quiescence in preterm pregnancies but does not adequately measure the intensity of contractions.

Adolescent

Cervical effacement: variation in belief among clinicians.

Cervical effacement may be described as a percentage or as residual cervical length in centimeters. For effective communication among clinicians, the percentage method requires agreement about the length of the uneffaced cervix. Variation in beliefs regarding cervical effacement and length was assessed among practicing obstetricians at a single medical center. The mean estimate for the length of the uneffaced cervix at term was 2.47 +/- 0.64 cm, with a range of 1-4 cm and a coefficient of variation of 26%. The mean estimate of physicians in private practice was significantly shorter (P less than .001) than that of faculty and house staff combined. There is the potential for miscommunication among physicians based on variation in beliefs about effacement. Adoption of the metric system for description of the cervix would eliminate hidden assumptions about cervical length and the concept of effacement.

Cervix Uteri

Prenatal detection of non-cardiac rhabdomyosarcoma.

The most prevalent soft tissue tumour in children is rhabdomyosarcoma. These tumours may develop within or outside of muscle anywhere in the body and at any age. We report what is apparently the earliest case of non-cardiac rhabdomyosarcoma detected prenatally.

Adult

A comparison of the effect of epidural, general, and no anesthesia on funic acid-base values by stage of labor and type of delivery.

The effect of epidural anesthesia on neonatal acid-base status, before, during, and after labor, was determined by review of funic blood-gas values from 142 women with normal term pregnancies and normal fetal heart rate patterns. Funic acid-base parameters were compared by type of anesthesia when stratified by mode of delivery (vaginal, cesarean section in the active phase of labor, or elective cesarean section). Use of epidural analgesia for vaginal delivery was associated with significantly longer labor, lower umbilical arterial pH, higher arterial PCO2 and arterial bicarbonate values. In women who had cesarean section in the active phase of labor, use of epidural anesthesia was associated with significantly lower arterial and venous PO2 values when compared with women who received general anesthesia. Patients who had elective cesarean section with epidural anesthesia had funic acid-base values similar to women who had general anesthesia. Epidural analgesia-anesthesia offers no clear advantage to the uncompromised term fetus.

Acid-Base Equilibrium

Transabdominal and transvaginal ultrasonography in the diagnosis of ectopic pregnancy: a comparative study.

Thirty-four patients believed to have ectopic pregnancies were examined by transabdominal and transvaginal ultrasonography. Twenty-five patients had tubal pregnancy confirmed operatively within 24 hours after ultrasonographic examination. In these cases adnexal findings highly suspicious for ectopic pregnancy were found in 68% of cases by transabdominal ultrasonography and in 84% by transvaginal ultrasonography. A distinct adnexal gestational sac was apparent in 32% of cases by transabdominal ultrasonography and in 64% of cases by transvaginal ultrasonography. Transvaginal ultrasonography was significantly more accurate (p less than 0.01) in identifying an adnexal gestational sac and allows more detailed adnexal imaging.

Abdomen

Spironolactone and estrogen-progestin therapy for hirsutism.

Sixteen women with hirsutism used spironolactone, 100 mg daily without interruption, plus norethindrone (1 mg) and ethinyl estradiol (35 mg) for 21 of each 28 days. Clinical improvement occurred in 11 of the 16 patients and also in an additional patient when the dose of spironolactone was increased to 200 mg daily. Spironolactone 100 mg daily plus norethindrone and ethinyl estradiol resulted in significant reduction in serum total testosterone, serum free testosterone, and percentage of free testosterone. Side effects were infrequent.

Drug Administration Schedule