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J S Soeldner

Publications and source records attributed to J S Soeldner.

201 records · Page 12Linked to original sources
PubMedDate not supplied

Activity of various endogenous compounds and pharmacologic agents at a glucose-oxidizing platinum electrode.

The specificity of a glucose-oxidizing platinum electrode system was investigated in vitro using selected metabolic compounds and a wide range of pharmacologic agents. Many compounds were found that either augmented or inhibited the glucose effect on the electrode system, but relatively few had substantial effects at reasonable plasma levels. Should the platinum electrode system be incorporated into an artificial beta cell for diabetic patients, graduated clinical trials might be necessary for every new medication taken by the patients.

Electrochemistry↗
PubMedDate not supplied

A noninvasive electromagnetic flowmeter.

The reliability and reproducibility of peripheral blood flow data obtained by a noninvasive electromagnetic flowmeter were tested using seven male and three female volunteers aged 15-46 years. Each subject was studied under multiple testing conditions in which time, subject's metabolic state, and electrode placement were varied. Each condition was repeated within 1 to 8 weeks to obtain test-retest data. Intraclass reliability coefficients of 0.864-0.998 were obtained on all pulsatile components both within a given measurement sessions and from one day to the next. The size and shape of the waveforms obtained from the data did not significantly differ from one another, thus indicating excellent reproducibility. No significant differences were found between data obtained from the right leg and that obtained from the left. The noninvasive electromagnetic flowmeter was found capable of providing reliable and reproducible data. For data analysis, the second of two consecutive curves seems to be the best choice for clinical assessment.

Adolescent↗