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Biomedical subjects

J S Wright

Publications and source records attributed to J S Wright.

At least 19 recordsLinked to original sources
PubMed1990

A 5-year study comparing a posterior composite resin and an amalgam.

Eighty class I and class II light-cured posterior composite resin restorations were compared with 43 class I and class II amalgam restorations during a 5-year period after placement. The results of this clinical study showed that both materials were satisfactory during the time period and that the only significant statistical differences are a poorer marginal integrity for the amalgam and a greater wear rate for the composite resin.

Adult↗
PubMed1990

Aortic compliance measured by non-invasive Doppler ultrasound: description of a method and its reproducibility.

1. Aortic compliance (expressed as percentage increase in lumen diameter for a pulse pressure of 10 mmHg) was calculated from the characteristic pulse wave velocity deduced from 'foot to foot' transit times of the blood flow pulse over a measured length of aorta. Two continuous wave Doppler ultrasound transducers were used: one insonating the root of the left subclavian artery, the other the abdominal aorta proximal to its bifurcation. Measurements were made after the subject had been supine for 5 min to achieve stable conditions. 2. Transit times were calculated on-line in real-time from the delay between the start of the systolic upstroke in the flow velocity sonograms recorded by the two transducers. 3. Within-visit variation was minimized by measuring over 45 cardiac cycles repeated three separate times and calculating an overall mean value for aortic compliance. A full measurement took 5-10 min. 4. Reproducibility of this overall mean value of aortic compliance was assessed at 1 month in 30 subjects (aged 60 +/- 7 years, mean +/- SD) and at 3 months in 23 different subjects (59 +/- 8 years). Aortic compliance values ranged from 0.1 to 2.0%/10 mmHg. 5. The mean paired difference between aortic compliance values was -0.02 between 0 and 1 months, and 0.03 between 0 and 3 months, with respective 95% confidence limits of -0.06 to 0.03 and -0.03 to 0.09 embracing zero, thus not differing significantly from baseline.(ABSTRACT TRUNCATED AT 250 WORDS)

Aorta↗
PubMed1990

Endocardial pacing through a prosthetic tricuspid valve.

We describe a patient in whom permanent endocardial pacing was accomplished by passage of the electrode through a porcine bioprosthetic tricuspid valve, thereby obviating the need for a second thoracotomy. After 8 years of follow-up, the patient continues to do well with satisfactory pacing and bioprosthetic valve function at the first change of pulse generator.

Bioprosthesis↗
PubMed1979

Late survival after coronary surgery.

One hundred and twenty-two patients have been followed for five to eight years after cardiac revascularization. The over-all mortality of 2% compares closely with the expected mortality of a normal population. Seventy percent of patients remain essentially angina free at an average follow-up period of six years. Late infarction, assuming all "coronary" deaths were so caused, occurred at a rate of 3.7% yearly.

Australia↗
PubMed1979

Deep hypothermic arrest: observations on later development in children.

Thirty-two children were reviewed following closure of ventricular septal defect in infancy. Fifteen had undergone continuous perfusion and 17 had been subjected to core cooling followed by deep hypothermic arrest. Parental and professional evaluations of intellectual and motor development, at periods between 7 and 72 months following operation, suggest that there is a higher incidence of developmental abnormality in the subgroup treated with deep hypothermic arrest.

Cardiopulmonary Bypass↗
PubMed1978

Excision of tricuspid valve with later replacement in endocarditis of drug addiction.

Staphylococcal endocarditis in a drug addict was controlled only after excision of the tricuspid valve. Total absence of the tricuspid valve was tolerated well for 18 months, at which time deteriorating liver function prompted the insertion of a bioprosthetic valve into the tricuspid ring. The haemodynamic and clinical results after two years of follow-up have been excellent.

Adult↗
PubMed1978

Ligation of the patent ductus. Technical considerations at different ages.

Over a 10 year period, 185 patients have been treated for patent ductus, including nine premature infants with a respiratory distress syndrome. Thirty-five other infants have had duct obliteration during the neonatal period, the incidation for surgery being intractable heart failure. Six of 18 adults had calcification or aneurysm in the duct region. three of these required extracorporeal circulation for duct control and closure. The remaining patients were from 1 to 18 years of age and underwent elective duct obliteration. Double ligation of the duct is regarded as the simplest, safest, and quickest technique generally applicable. Special techniques are required for fragile, broad, calcified, hypertensive, and conical ducts.

Adolescent↗
PubMed1977

Heart valve replacement by porcine aortic valve (Hancock prosthesis).

Glutaraldehyde preservation of heterograft valves has increased their durability. Sixty-nine Hancock prostheses have been implanted, 30 in the mitral position and 39 in the aortic position. Anticoagulants have not been administered. There has been one important thromboembolic complication and periprosthetic mitral incompetence has occurred in three instances, but prosthetic incompetence has not developed. Two asymptomatic aortic diastolic murmurs have been noted. After a follow-up ranging between two and 19 months, it appears that the Hancock prosthesis offers a valuable alternative to mechanical valve replacement and anticoagulants are not required as a routine.

Adolescent↗
PubMed1977

Dopamine hydrochloride (Intropin) and open-heart surgery: results of a clinical trial.

Dopamine hydrochloride (Intropin) has been used in the postoperative management of open-heart surgical patients, both children and adults. It has been associated with a very low incidence of undesirable responses and a high frequency of circulatory improvement associated with diuresis. Its administration requires careful control of infusion rate and measurement of response. In the dosages employed, it has been free of most of the undesirable side effects of other commonly used catecholamines.

Adult↗
PubMed1977

Technical considerations in the use of the membrane oxygenator (Lande'-Edwards) for open heart surgery.

Experience has shown that successful cardio-pulmonary bypass depends upon an efficient oxygenator which causes minimum blood damage. Experience with 1,600 Lande'-Edwards membrane oxygenators in more than 1,000 patients has led to the development of a simple and safe routine for their use in open heart surgery. The circuitry, method of preparation for perfusion, and management of perfusion are described in detail.

Adult↗
PubMed1976

Current management of coarctation of the aorta.

A series of 55 surgically treated cases of coarctation of the thoracic aorta is presented with an operative mortality of 5-4%. The problems encountered in infants are discussed and postoperative complications in adults and children detailed. The advantages of patch graft aortoplasty over resection and end-to-end anastomosis are described.

Adolescent↗
PubMed1976

The influence of surgery on survival of patients with angina.

Myocardial revascularization surgery has proved most effective in relieving angina pectoris. Its influence on the survival of patients with coronary atherosclerosis, however, remains a contentious subject and one which may not be finally settled for years. The follow-up results of the first 196 patients to undergo direct coronary artery surgery at the Prince Henry Hospital support those who claim increased longevity as one of its benefits.

Adult↗