Biomedical subjects
J SHEWELL
Publications and source records attributed to J SHEWELL.
THE COMBINATION OF HYPOXIA AND CYSTEAMINE TREATMENT IN PROTECTING MICE FROM WHOLEBODY IRRADIATION.
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Maximum protection of mice against 8-MeV electron irradiation.
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The catabolism of 131I-labelled homologous gamma-globulin in normal, hyperthyroid and hypothyroid rats.
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The influence of the thyroid gland on the catabolism of 131I-labelled homologous gamma-globulin in the guinea-pig.
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The influence of the thyroid gland on antitoxin production in different species.
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The activity of different steroids in producing thymic involution.
The assay method for corticotrophin, in which the involution of the thymus of the nestling rat is measured, can be applied successfully as a quick and simple screening test for biologically active corticosteroids. The sensitivity of the test is such that injection of a standard dose of cortisone acetate produces different results when made up in different media, or injected by different routes. A standard procedure for dispensing and injecting the steroids has therefore been adopted. Of the steroids investigated, it is noticeable that those possessing marked thymolytic activity are also steroids with therapeutic properties.
A species difference with regard to the effect of cortisone acetate on body weight, gamma-globulin and circulating antitoxin levels.
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The influence of the thyroid gland on the production of antitoxin in the guinea-pig.
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The influence of the thyroid gland on sensitivity to tuberculin in guinea-pigs.
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