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Biomedical subjects

J Sabin

Publications and source records attributed to J Sabin.

10 recordsLinked to original sources
PubMed1994

A prospective analysis of autograft versus allograft in posterolateral lumbar fusion in the same patient. A minimum of 1-year follow-up in 144 patients.

STUDY DESIGN: One hundred forty four patients who underwent lumbar spine fusions had autografts placed on one side as a control and on the opposite side one of the following types of graft material was placed: iliac autograft, demineralized cancellous chips, demineralized cortical powder, demineralized cortical powder mixed with autograft, or mineralized cancellous chips. Alar anteroposterior and lateral postoperative radiographs were reviewed by three independent observers and graded for quality of fusion mass bilaterally. The follow-up was 14 to 27 months. OBJECTIVES: This study evaluated the efficacy of various types of ethylene oxide-sterilized allograft bone used for spine fusions and compared them with autograft iliac bone in the same patient. SUMMARY OF BACKGROUND DATA: Previous studies comparing autograft with allograft showed poorer fusion rates with allograft with posterior fusions. Most of the previous studies included smaller numbers of patients. No previous studies compared ethylene oxide-treated allograft with autograft. RESULTS: An analysis of the radiographs at a minimum of 1 year postoperatively revealed significantly lower values when allograft alone or in combination with autograft was used in comparison to autograft alone. CONCLUSIONS: Ethylene oxide-treated allograft is inferior to autograft and should not be used for posterior lumbar fusions.

Adult↗
PubMed1989

The small acoustic tumour; a chance to preserve hearing.

The authors report their experience in the surgical management of small (less than 1.5 cm diameter) acoustic neuromas. Twenty-nine patients were treated. They had suffered symptoms of unilateral eighth nerve dysfunction on average for 37 months. High resolution CT with iv contrast was the primary investigation. In equivocal cases, air meatography was performed. All operations were performed by the senior author (LS). All tumours were totally removed, there were no deaths and all patients had an excellent result. There were 6 complications (CSF leak 3; meningitis 2; deep venous thrombosis 1). The facial nerve was preserved in 26 cases (and functioned adequately in all) and the cochlear nerve in 62%. In 4 cases with hearing pre-operatively, the decibel loss was the same or less post operatively. In 8 cases speech discrimination remained above 35%.

Adolescent↗
PubMedDate not supplied

The ethics of accountability in managed care reform.

Two notions of accountability embodied in proposals to reform managed care have different ethical implications. Market accountability requires plans to inform purchasers and consumers about performance and options, in theory legitimizing limits to care through consumer choice. Recognizing the limits of consumer choice, accountability for reasonableness requires that the rationales for limits to services be public and be based on reasons or rules that "fair-minded" people can agree are relevant to pursuing appropriate patient care under necessary resource constraints. Accountability for reasonableness educates clinicians and patients about the need for limits and empowers a more focused public deliberation in which ultimate authority for limiting care rests with democratic processes.

Consumer Advocacy↗