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Biomedical subjects

J Sackett

Publications and source records attributed to J Sackett.

5 recordsLinked to original sources

Computerized intravenous arteriography: a technique for visualizing the peripheral vascular system.

A unique method of computerized fluoroscopic enhancement allows direct visualization of the entire vascular system by intravenous injection of standard contrast agents, thereby avoiding the need for arterial puncture or hospitalization. This technique has been used to satisfactorily visualize the intra- and extracranial carotid and vertebral arteries, the aortic arch and upper extremity vessels, the abdominal aorta and its branches, as well as lower extremity vasculature. Although the technique is still under development, occlusions, stenoses, ulcerated plaques, and aneurysms have been visualized. Qualitative evaluation of these studies indicates a promising correlation with standard arteriography. This technique has great promise as a method of diagnostic screening in the management of peripheral vascular disease.

Aneurysm↗

The binding of organic ions to phospholipid bilayers.

The binding of organic anions and cations, mainly tetraphenylboride and tetraphenylarsonium, to phospholipid membranes has been studied using an NMR method. Binding is appreciable and is affected by cholesterol in the membrane and counterions in solution. The passage of the organic anions through the membrane has also been followed. These measurements indicate that it is naive to use organic anions to measure membrane potentials in a simple manner.

Arsenicals↗

Doppler ultrasound evaluation of extracranial cerebrovascular disease.

Carotid Doppler examination was compared with arteriographic findings in 125 patients. The results demonstrated exact correlation in 87% of vessels studied. Clinically significant errors occurred at a rate of 4.5%. Clinically insignificant errors (8.5%) were usually the result of wall disease being mistaken for nonhemodynamically significant stenosis.

Brain Ischemia↗