PubMed Health⌕ Search

Biomedical subjects

J Sadé

Publications and source records attributed to J Sadé.

133 records · Page 8Linked to original sources
PubMedDate not supplied

Meniere's disease in infants.

We described 3 patients who, from early infancy, evidenced attacks of vomiting associated with fluctuating hearing loss, culminating in bilateral severe sensorineural hearing loss. The patients suffered from Meniere's disease, according to all clinical yardsticks. The patients described by us were at first diagnosed and treated for gastroenteritis or meningitis. Meniere's disease was not suspected. We want to point out that Meniere's disease, though usually presenting itself at middle age, may well start in childhood as well as in infancy, and should be suspected whenever vomiting, without diarrhea, is associated with some hearing loss at any age--no matter how young the patient is. It is also possible that some sensorineural hearing losses in late childhood or adulthood are in effect the end result of burnt-out Meniere's disease--as our second case presented himself.

Age Factors↗
PubMedDate not supplied

The human Eustachian tube lumen in children. I. The isthmus.

A study of Eustachian tube measurement in infants and children is presented. The study comprised 53 Eustachian tubes from normal temporal bones and 17 Eustachian tubes from temporal bones harbouring acute and secretory otitis media. The temporal bones underwent histologic serial sectioning. The lumen of the Eustachian tube isthmus was measured with the aid of a grid mounted on a microscope. These measurements show: A) the Eustachian tube isthmus lumen does grow and enlarge slightly with age; B) each age group presents a considerable range in area, compatible with a natural biological distribution; C) no statistical difference was found in the size of isthmus lumens obtained from temporal bones which had been affected by acute or secretory otitis media, when compared with lumens of Eustachian tubes coming from non-pathological ears. This comparison took into consideration both age and physiological distribution.

Age Factors↗
PubMedDate not supplied

Diurnal fluctuations of middle ear pressures in atelectatic ears.

The tympanic membrane of 18 atelectatic ears was examined before and immediately after nocturnal sleep. On the patients' awakening, eight (44.4%) of these ears presented a spontaneous disappearance of the atelectasis. The original atelectatic state reappeared thereafter within 75 min (on average). This time corresponds to diffusion into the circulation of a gas mixture similar to air. The spontaneous autoinflation of atelectatic ears cannot therefore be explained by nocturnal CO2 diffusion into the middle ear, as CO2 would rediffuse in a matter of 5 min. Nocturnal relaxation of the Eustachian tube muscles with opening of the tube and influx of air into the middle ear is the suggested mechanism which may be at the root of the phenomenon described in this study. The phenomenon itself emphasizes the fluctuating nature of atelectatic conditions, and raises questions regarding the cardinal role played by swallowing in aerating the middle ear.

Adult↗
PubMedDate not supplied

The eustachian tube muscles in otitis media. A comparison between eustachian tube muscles in healthy and inflamed ears.

The cross-sectional area of the tensor palati (TP) and levator palati (LP) muscles in the mid-portion of the Eustachian tube was measured in serially sectioned histological specimens of 35 temporal bones (TB). 17 of the TBs presented acute or secretory otitis media. The other 18 TBs showed no evidence of inflammatory disease. No significant differences were found between the mean sizes of the muscles coming from TBs with acute and secretory otitis media and of those from TBs without signs of inflammation. The cross-sectional area of the LP was found to be significantly larger than that of the TP. These results raise the question as to the actual role of the muscles' size in inflammatory middle ear disease in infants and children, and as to the role of the LP.

Acute Disease↗
PubMedDate not supplied

Modified radical mastoidectomies as gas pockets.

An analysis of 45 adult ears which underwent a modified radical mastoidectomy showed: (a) in practically all these ears a variable amount of air was present behind the tympanic membrane; (b) this air was in continuation with the Eustachian tube; (c) two-thirds of the ears showed a collapse of part of the tympanic membrane--located predominantly in the posterior superior parts of the middle ear. These findings indicate that these atelectatic ears are gas pockets which are not closed, yet suffer from an imbalance of gas diffusion--from or into the middle ear.

Air↗