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Biomedical subjects

J Saint Martin

Publications and source records attributed to J Saint Martin.

12 recordsLinked to original sources
PubMed1998

[Idiopathic thrombocytopenic purpura: long-term outcome].

BACKGROUND: Idiopathic thrombocytopenic purpura (ITP) has usually an excellent prognosis even when no specific therapy is given. We studied, in 1996, the outcome of 87 patients with ITP observed between 1973 and 1995. PATIENTS AND METHODS: These 87 cases represented all the thrombocytopenic purpura observed during 23 years in the same pediatric unit not specialized in hematology. The outcome of these children was investigated in 1996 by phone or writing to the patients themselves or to their physician. Adequate information was obtained for 63 patients (72.4%). RESULTS: Two cerebral hemorrhages were observed, one was lethal while the other, observed after several years of course, healed completely. All these patients became free from clinical signs but 11 were not cured in 1996. None of these 63 patients had developed autoimmune disease. One patient died in a traffic accident, his thrombocytopenic purpura had been cured. CONCLUSION: In spite of two cerebral hemorrhages, ITP remains in the great majority of cases a benign disease not requiring grave therapeutic decisions.

Adolescent↗
PubMed1998

[Adoption and chronic hepatitis B carrier state].

AIM: Because there are few adoptable children in France, parents, for the last 20 years, have turned to international adoption. Alerted by the generally poor health of these children, we paid particular attention to their health problems and especially to infection by hepatitis B virus (HBV). POPULATION AND METHODS: The 60 internationally-adopted children seen from June 1993 to June 1997 were included in this study. All had hemogram and serum iron dosage, and search for intestinal parasites and tuberculosis was performed in each child, as were HBs antigen and HBs antibody screening. When HBs antigen was positive, HBe antigen and antibodies, HBV DNA and hepatitis C and delta serology were also studied. RESULTS: Six out of the 60 children were HBV chronic carriers. The six presented HBs antigen and five out of the six presented viral DNA. One child was co-infected with delta virus. Serum aminotransferase was normal in three children and increased in the three others. DISCUSSION: Some internationally adopted children are exposed to chronic infection by HBV. This concerns children coming from countries known for the high frequency of the disease, but also children with long stay in Eastern European nurseries. Chronic HBV carriage puts the child, as well as the family and other children in institutions and/or schools at risk, thus necessitating preventive measures.

Adoption↗
PubMed1991

[Bilateral newborn testicular torsions].

A case of bilateral spermatic cord tension in a neonate is reported. Clinical findings are compared with those in 22 previously published cases. Obstetrical history is usually unremarkable. Torsion occurs prior to birth or immediately after birth. The two cords are involved simultaneously or successively. Edema of the scrotum is found in recent spermatic cord tension, whereas subsequently the tests are extremely hard and occasionally severely atrophied. Prognosis is poor since castration or poor testicular viability was the outcome in most cases.

Castration↗
PubMed1989

[Overdose of anticholinergic agents and confusional syndrome].

We report a case of behavior disorders due to ingestion of two closely spaced oral doses of chloride of oxybutynin in a six-year-old. This drug is not indicated in isolated enuresia. More rigid dosage schedules with longer time intervals between doses are needed.

Child↗
PubMed1985

[In utero death of one twin and cerebral complications in the surviving twin].

When one of two twin foetuses dies in utero, the survivor may present with a number of abnormalities, including severe lesions of the nervous system. These lesions are of vascular origin and seem to be due to tissue emboli from the dead foetus. Monochorionic pregnancies are those at the highest risk of this pathology. The surviving twin must be examined both clinically and by ultrasonography.

Brain Diseases↗
PubMed1982

[Cerebral lesion in surviving twins (author's transl)].

In a monozygous twin pregnancy, one twin was still-born while the other presented with a severe encephalopathy with seizures, diffuse hypotonia and microcephaly. CT-scan showed cystic lesion in the brain. This type of lesion should be investigated in each "surviving twin".

Brain Diseases↗