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Biomedical subjects

J Salmela

Publications and source records attributed to J Salmela.

5 recordsLinked to original sources

Effects of progressive exercise on attentional focus.

To replicate 1986 work of Salmela and Ndoye on whether physical arousal from riding a stationary bicycle led to narrowing of attentional focus 17 subjects responded to a verbal 5-choice RT task while pedalling to exhaustion. Increased heart rates with increased physical stress (bicycle resistance increased) was not associated with narrowing of attention. When heart rates were 160 and 180 bpm, RTs to stimuli peripherally located to the right were slower than central ones. Further evaluation is required.

Adult

Midazolam vs lorazepam and placebo as hypnotic premedication before surgery. A controlled, double-blind study.

The efficacy of midazolam vs lorazepam and placebo was studied in 60 patients in a comparative, double-blind study. Midazolam 15 mg and lorazepam 2.5 mg were given orally in a single dose the night before operation. Sleep latency was shortest on midazolam but the mean duration of sleep longest on lorazepam. Four patients on lorazepam complained of headache and one reported tinnitus. Three patients receiving midazolam complained of headache. Headache was observed also in one patient given placebo and another experienced tachycardia. Midazolam administered the night before surgery is a preferable hypnotic for transient insomnia caused by preoperative anxiety.

Adult

Clostridium septicemia following biliary surgery in a gastrectomized patient.

A 75-year-old woman was subjected to biliary surgery 38 years after partial gastrectomy for ulcer. There was a history of gallstones of 10 years duration, pentagastrin-resistant achylia, cholecystolithiasis and choledocholithiasis complicated by stenosis of papilla of vater, cholecystitis and pancreatitis. Peroperative cholangiography and biliary tract surgery were performed. On the third postoperative day heavy jaundice and hemolysis developed, leading to death of the patient. Culture of bile taken at operation revealed strains of Clostridium perfringens and Escherichia coli. Autopsy showed a picture of gas gangraena of the liver and Clostridium septicemia. The role of achylia, blind loop, and biliary obstruction in bile surgery is stressed.

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