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Biomedical subjects

J Sarubin

Publications and source records attributed to J Sarubin.

8 recordsLinked to original sources
PubMed1983

[Pain relief with morphine, intrathecally or peridurally?].

We investigated pain relief following 1-2 mg morphine intrathecally applied in 7 patients with cancer pains and in 5 patients with multiple rib fractures (group 1). For postoperative pain relief (group 2) we applied 1-2 mg morphine intrathecally in 26 patients immediately before the induction of the anaesthesia. In 30 patients we applied 4 mg morphine epidurally in 10-20 ml saline solution for postoperative pain relief (group 3). In the first group the duration of the pain relief was 25,2 hours, in the second group 31 hours and in the third group 15,7 hours. In the second group a respiratory depression occurred in 3 cases and was successfully treated with naloxon. In the third group a bladder disorder occurred in two cases. Because of the risk of respiratory depression following intrathecally applied morphine, we recommend the epidural way of application.

Analgesia↗
PubMed1983

[A new plastic-bag transfusion set for dilution of erythrocyte concentrates].

A new transfusion set which contains 100 ml of 0.9% sodium chloride solution to resuspend packed red blood cells is described. The advantages of the system are--the technique is simple and hygienic, it contains an optimal quantity of suspension solution, and there is no danger of air embolus occurring. The rheologic properties of the then diluted red cell concentrates are very good, and allow for a mass transfusion. This new system affords the wider use of packed red blood cells, and it will probably contribute to the abolition of the practically obsolete transfusion of whole blood even for surgical patients.

Blood Transfusion↗
PubMed1982

[Increased requirement of alcuronium in burned patients].

We determined using the visual semi-quantitative method (train of four; Myotest) the initial dose of Alloferin (alcuronium) needed for complete neuromuscular relaxation during nitrous oxide/oxygen anaesthesia with fentanyl and diazepam in 12 burned patients operated for excision of necrotic skin and skin-graft on the 7th to 21th day following thermal injury. In a control group of 20 general surgery patients the initial dose of Alloferin was determined in the same way. The requirements of Alloferin was in the control group 15 mg (0.21 mg/kg) and in the group of burned patients 23.75 mg (0.35 mg/kg). The difference of the requirement of Alloferin was statistical significant between the two groups (p: 0.1%). The total protein and the beta globulin were significant higher in the control group. A extrajunctional spread of acetylcholine receptors might explain the increased requirement of Alloferin in burned patients.

Adolescent↗
PubMed1981

[Serum potassium rise following depolarizing muscle relaxants in immobilized patients (author's transl)].

We investigated the time-course of serum potassium levels after depolarizing muscle relaxants in immobilized patients of our critical care unit. It could be demonstrated that the duration and the degree of immobilisation determines the increase of serum potassium after application of succinylcholine or Imbretil (hexacarbacholine). In burned patients or patients with cord-lesions an earlier increase of serum potassium could be seen than in other immobilized patients. The potassium time-course shows a difference between short acting and long acting muscle relaxants. A block of repolarisation and its possibility of generating is discussed.

Burns↗
PubMed1981

[A quick method for estimating blood haemoglobin concentrations (author's transl)].

Blood haemoglobin concentrations were estimated in 30 patients in a surgical intensive care unit. The methods used were the standard laboratory technique (photometer Medico) and a bed-side method (Compur M 1000). Comparison of the data showed very good correlation (correlation coefficient: 0.993). This rapid method is very convenient for haemoglobin estimations in surgical emergencies in the intensive care unit.

Adult↗
PubMed1980

[Morphine intrathecally - in postoperative and cancer-induced pain (author's transl)].

Morphine 2 mg was injected directly into the intrathecal space in 33 patients. In the nonoperative group (group I) morphine was given with 2 ml saline solution; in the operative group (group II, 21 patients) morphine was given with 2 ml 10% glucose solution immediately before induction of anaesthesia. The onset of pain relief occurred after 12 to 35 min and the duration of analgesia was 14 and 18 35 min and the duration of analgesia was 14 and 48 hours. In group II we observed in respiratory depression 3 cases and in one case bladder insufficiency after morphine. In group I bladder insufficiency occurred in 2 cases. The disturbed bladder function recovered spontaneously in a few hours after morphine application. Respiratory depression was treated successfully with naloxone.

Adult↗