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J Scherrer

Publications and source records attributed to J Scherrer.

7 recordsLinked to original sources
PubMed1979

Projections of the common fur of the muzzle upon the cortical area for mystacial vibrissae in rats dewhiskered since birth.

In normal adult rats, the mystacial vibrissae and the common fur of the snout project at different loci on the SI cortex. The surface area of the normal fur projection is 0.8 mm2, whereas the vibrissa field amounts to 3-4 mm2. In rats dewhiskered since birth, the vibrissa area can still be identified through the projections from ipsilateral vibrissae (undamaged side). It is shown that in the absence of the vibrissae since birth, the vibrissa area, and this alone, is invaded by projections from the contralateral fur (damaged side).

Animals↗
PubMed1975

[Study of viral specific RNA synthesis in FHM and RTG-2 cells infected with infectious pancreatic necrosis (IPN) virus (author's transl)].

In FHM and RTG-2 cells infected with IPN virus two types of viral directed RNAs where isolated in the presence of 0.5 mug/ml actinomycin D. One type, sedimenting at 14-15 S in sucrose gradients, was shown to be resistant to digestion by pancreatic RNase and did not precipitate in presence of lithium chloride 2 M. Furthermore the molecules sedimented in the same way as the double stranded RNA extracted from purified virions. The second type of RNA, sedimenting at 23-24 S, was sensitive to RNase and was precipitable by LiCl, indicating that it was single-stranded. Additionally it was shown by polyacrylamide gel electrophoresis that this type of RNA resolved into four peaks. The single stranded 23-24 S RNA was detectable in cells from the third hour following infection; it represents the major portion of total viral directed RNA that was synthesized during a cycle of replication. The synthesis of both single stranded and double stranded RNA increased exponentionally until the 7th hour post-infection and began to decrease at about 10 hours.

Animals↗