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Biomedical subjects

J Schmitt

Publications and source records attributed to J Schmitt.

At least 19 recordsLinked to original sources
PubMed1979

[Aquatic myxobacteria (Sporocytophaga cauliformis) and the order "Myxobacterales" (author's transl)].

The indicator function of aquatic myxobacteria for the purpose of evaluating drinking water quality as well as their occurrence in sewage effluent make it desirable to describe these hitherto little known organisms in more detail. To this end, a comparative investigation of anaerobic myxobacteria of the genus Sphaerocytophaga, two typical representatives of the Order Myxobacterales (Myxococcus fulvus, Sporocytophage cauliformis), and a strain ov Vitrepscilla (Vitroescilla proteolytica) was undertaken. With respect to culture morphology, the migratory fringe surrounding colonies of Sphaerocytophaga similar to the other strains studies was a prominent characteristic. In particular, the similarity with colonies of Sporocytophaga cauliformis was apparent. The gliding motility typical of Sphaerocytophaga could be demonstrated in all of the strains investigated. Scanning electron micrographs revealed an amorphous layer of slime covering the cell surfaces in all strains compared in this study, thus excluding the existence of more rigid organelles of locomotion. Taxonomically, the anaerobec myxobacteria of the oral cavity (Sphaerocytophaga) belong to the Order "Myxobacterales" and not the "Eubacterales", i.e., to the genus Fusobacterium. This is clearly suggested by their motility lacking flagella and, above all, by their cell morphology which differs from the Eubacterales.

Culture Media↗
PubMed1979

[Endocrine polyadenomatosis: progressive neurocristopathy (author's transl)].

Endocrine polyadenomatosis forms but a part of the larger group of neurocristopathy disorders. This term includes those affections due to lesions of cells, tissues, or organs derived from the neural crest. The common origin of the various neuro-endocrine cells within the neural crest suggests that there is a denominator of embryologic pathogenicity for the different polyendocrine affections. Knowledge of these is essential for early diagnosis of the different neuro-endocrine lesions, together with a systematic search for any familial associations.

Acromegaly↗
PubMed1979

[Is the primary lesion in Behcet's disease a venous "tropism" vascularity? (author's transl)].

The authors studied eight cases of Behcet's disease, all of which were characterized by different degrees of phlebitis disorders. They also reviewed the anatomical and clinical features of a similar type, reported in the published literature. They stress the frequency and severity of changes in the veins in the localization of the various symptomatic lesions of the affection. From these results, they conclude that the primary lesion in this disease could be a phenomenon of vascularity of mainly venous-"tropism" which would explain the proteiform clinical features of Behcet's aphthosis.

Behcet Syndrome↗
PubMed1978

Genetic variation of aldehyde dehydrogenase in primates.

Genetic variation of aldehyde dehydrogenase has been demonstrated in catarrhine primates. The results are in accordance with the formal genetic interpretation: three alleles, AldDH1, AldDH2, AldDH3, at the gene locus AldDH. Obviously, the allele AldDH1 has undergone fixation in Homo and Hylobates, the allele AldDH2 in Macaca and Papio, and the allele AldDH3 in Cercopithecus.

Aldehyde Oxidoreductases↗
PubMed1978

A comparison of the healing processes in uremic and parallel-fed rats.

The effect of nutrition on the healing capacity of uremic rats was investigated. Wound tensile strenth and the amount of collagen formation in polyvinyl sponges implanted subcutaneously were compared in a group of uremic rats and a group of nonuremic rats parallel-fed an identical diet and caloric intake. Wound tensile strength in the parafed rats closely and significantly approximated that in the uremic snimals conpared to the stronger wounds in the controls. A correlation was also noted for collagen accumulation in the uremic and parafed groups. This experiment lends further evidence to support the theory that the mechanism of action for the shown poor healing associated with uremia is based on the poor state of nutrition in the uremic animal.

Animal Nutritional Physiological Phenomena↗
PubMed1978

[The myocardiopathies of hereditary neuro-muscular diseases].

This joint work has studied the cardiomyopathies occurring in hereditary neuro-muscular disorders (270 cases). The Duchenne type of disorder (74 cases) was responsible for asystole (4 cases), for cardiomegaly, and especially for abnormalities of the ECG (59 cases)--Q waves and large R waves in V1 and V6. The cardiomyopathy was of the hypokinetic type, with histological evidence of degeneration of the myocardial fibres. Dystrophia myotonica of Steinart (23 cases) caused conductive disorders (17 cases) which were either atrioventricular or intra-ventricular or both. Studies of the His pathway confirmed that these abnormalities were more diffuse in 5 cases. The main histological feature was interstitial fibrosis. There was a high risk of sudden death; ECG follow-up should be close. Friedreich's disease (20 cases) in its complete form led to later development of obstructive cardiomyopathy, with a systolic ejection murmur, cardiomegaly, and abnormalities of the ECG--left ventricular hypertrophy in the vertical axis, right ventricular and septal hypertrophy, repolarisation disorders similar to those found in coronary artery disease. Histology showed hypertrophy with degeneration of the myocardial fibres and interstitial fibrosis. This complete form was rare (7 cases out of 20); on the other hand, ECG abnormalites were very common (16 cases out of 20). The authors have tried to study the relationships between primary cardiomyopathies (50 cases) and peripheral neuromuscular disorders. 17 of the 39 peripheral muscle biopsies were abnormal, but a well-defined muscular dystrophy could not be found in them.

Cardiomyopathies↗
PubMed1977

[Landouzy-Dejerine syndrome. Evolution of the concept of facio-scapulo-humeral amyotrophia].

Detailed analysis of the literature and the study of personal cases have led the authors to propose a new concept for facio-scapulo-humeral dystrophy. They consider it to be a syndrome, embracing under the same clinical picture both muscular disease (classical hereditary muscular dystrophy, congenital and acquired myopathies) and neurological disease (in particular progressive pseudomyopathic amyotrophy).

Facial Muscles↗
PubMed1976

[Hansen's neuritis in the form of pseudysyringomyelia. Clinical, diagnostic and therapeutic consideration a propos of 3 cases].

Three cases of neuropathic leprosy (one Moroccan, two non-colonial immigrants) enable attention to be drawn to two aspects of theproblem of Hansen's neuritis: 1) such cases should no longer be considered exceptional, infection occuring in countries where leprosy is endemic but the disease developing years later in any country; 2) among the various neurological aspects of neuritis due to Hansen's bacillus, great stress is laid on sensory disorders of the syringomyelic type, with thermalgesic dissociation; although these symptoms have been considered typical (our three cases are an illustration of this), they seem to occur fairly rarely and are the cause of difficulties in diagnosis as it is the last thing one would think of. Treatment of these neural forms is not encouraging, in spite of a therapeutic arsenal which in theory is considered effective.

Female↗
PubMed1976

[Computer tomography in ophthalmology (author's transl)].

The computer-aided tomography system (EMI-Scan) represents a new X-ray method in neuroradiology. Some cases of various space occupying retrobulbar orbit processes are presented, and it is demonstrated that this method is also well suited to the diagnosis of orbit diseases. Physicotechnical basis, technique of examination, the indication for computer tomography and the diagnostic possibilities are described.

Adolescent↗
PubMed1976

[Nosographic approach of heriditary myopathies. Attempt at classification and diagnosis by means of erythrocyte cholinesterase and serum pseudocholinesterase analysis].

An original biological study involving assessment of red cell cholinesterase and serum pseudo-cholinesterase activity has given the authors a new approach to the classification of progressive muscular dystrophy: as a result, it has become possible to isolate Duchenne dystrophy and the carries of this disease and to distinguish them from cases of Becker's disease. Also, Leyden-Möbius dystrophy appears to deserve the name as it differs from limb-girdle dystrophy. Finally, there is a case to be made for classifying separately, because of its special biological characteristics, Steinert's myotonic dystrophy.

Butyrylcholinesterase↗