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Biomedical subjects

J Schoenmackers

Publications and source records attributed to J Schoenmackers.

At least 19 recordsLinked to original sources

[Technique of comparative angiographic and morphologic examination of the heart and pulmonary circulation (author's transl)].

Morphological changes of the cardiovascular system, e.g., due to congenital or acquired valvular diseases, cannot be analysed, evaluated or documented sufficiently by traditional gross pathological examination alone. The investigation of gross specimens of the heart and lungs is limited mainly to the inspection of the natural and cut surface, whereas postmortem angiograms allow three-dimensional examination of the vasculature even stereoscopically. Small vessels, e.g., bronchial arteries and anastomoses can easily be demonstrated by routine methods. The specimens can be formalin-fixed and contrasted by special techniques. Formalin-fixed and contrasted specimens of the heart and lungs are especially useful in the search for occult bleeding sources, emboli in chronic recurrent pulmonary embolism, and the investigation of the vascular system in pneumoconioses, primary and secondary tumors as well as in the analysis of the pulmonary vasculature in cases of defect of the ventricular septum and cor pulmonale. The basic morphology of computerized transaxial tomography can be studied from these sliced heart-lung specimens.

Angiocardiography↗

[Morphologic consideration of heart failure (author's transl)].

The left ventricle in left heart failure can be elliptical, spherical or funnel shaped. There is no firm correlation between the different shapes and the hemodynamics. Left ventricular failure results in dilatation, deformation and loss of funnel function of the left atrium. In more advanced stages of left ventricular failure the pulmonary veins become coiled, dilated and narrow stepwise instead of the normal harmonic narrowing to the periphery. The pulmonary parenchyma exhibits fibrosis and septal siderosis at that stage. Heart failure cells can be observed frequently. In later stages, when pulmonary arteries and the right ventricle is involved, secondary global heart failure develops. Right ventricular failure may lead to necrosis of liver cells with jaundice and elevated levels of liver specific enzyms. Primary global failure has no hemodynamic consequences on the pulmonary circulation, as long as left and right ventricular failure are of equal severity. If one form prevails, the clinical picture will be that of left or right ventricular failure respectively.

Adolescent↗

[Anatomy and pathology of the tricuspid valve (author's transl)].

Anatomy and pathology of the tricuspid valve are presented in a short survey. Annulus fibrosus and leaflets are less firm than those of the mitral valve, whereas the tricuspid orifice is larger than the mitral orifice. Isolated tricuspid disease - congenital or acquired - occurs only rarely. Functional non organic tricuspid regurgitation is clinically of primary importance.

Animals↗

[Radiographic pattern of iodine contrasted arteriosclerotic vascular changes. Analysis and documentation (author's transl)].

Vessels as well as soft tissues can be contrasted in a solution of 10 percent formaldehyde and sodium iodate so that structural details can easily be identified by X-ray. Atheromatous plaques, ulcers and calcifications are demonstrable by comparing X-ray films of contrasted and uncontrasted vessels. This methods allow a quick investigation of vascular walls and of other tissues.

Aortography↗