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Biomedical subjects

J Schroff

Publications and source records attributed to J Schroff.

4 recordsLinked to original sources

Identification and diagnostic evaluation of hearing impairments in early childhood in German-speaking infants.

The present study was devised to gather epidemiological information to aid in understanding the etiology, identification, and management of children with permanent hearing losses in Lower Saxony as a defined geographical area of Germany. All infants and preschool children were identified in the Department of Phoniatrics and Pediatric Audiology during a 1-year period (October 1994 until October 1995). Forty-four hearing-impaired children were identified, of whom 41 (93%) had sensorineural losses and 3 had pure conductive losses. Thirty-two children (73%) had bilateral hearing impairments. The causes of hearing loss were unknown in 17 children (39%). The median age of identification for the study group was 32 months, with a median age of 35.5 months when fitting hearing aids. Severity of hearing loss was inversely associated with age of identification. Prelingually deaf children had the worst comprehension levels of all children tested psychologically. Results were tabulated and special references to other studies were discussed. Our findings show again that the successful out-come of speech and language development depends on early identification and management of the hearing loss, and on continued assessment of the progress of habilitation. These require a basic assessment of the stage of language development (in perception and expression) as relevant rehabilitation measures. The next step is the treatment of existing linguistic deficits followed by retests at regular intervals.

Child, Preschool↗

[Quality control in pediatric hearing aid fitting].

Specific hearing aid selection and careful fitting are essential for successful rehabilitation of hearing-impaired children. For this reason the different hearing aid types prescribed, the type and frequency of hearing aid insufficiencies reported and the effectiveness and regularity of our follow-ups were studied evaluating 253 followup exams in 39 children (71 ears) suffering of a sensorineural hearing loss, including all degrees, supplied with a behind-the-ear hearing aid. Most of the devices had been prescribed outside our department on an initial trial basis. After critical evaluation, the number of hearing aid types was reduced from 33 to 23 when corresponding devices failed to match well with the degrees and types of hearing losses present. A further decrease in hearing aid types could not be achieved as a consequence of many being already end-prescribed. Insufficiencies (n = 222) were found in 60% of the hearing aid evaluations: 59% involved dynamic hearing aid adjustments requiring better amplification (37%), distortion (18%) and dynamics (4%). Additionally, 16% affected hearing aid function and another 16% form (9%) and material (4%) of the otoplasty and the tube (3%). The last 9% of the deficiencies concerned the potentiometer cap: it hadn't been fitted in about half of the cases and had been lost in the other half despite being needed. Routine followup evaluations of the hearing aids occurred regularly in 76% of the cases with an effectiveness of 73%. Our results confirm the importance and necessity for pedaudiologic qualitative hearing aid controls in children.

Audiometry, Evoked Response↗

Neutrophil enzyme activities in rheumatoid inflammation.

This study analyzed the neutrophils and sera of patients with rheumatoid arthritis and of normal controls. No significant differences were found in the activities of the granular enzymes beta-glucuronidase and lysozyme or the cytoplasmic enzyme lactic dehydrogenase (LDH). Normal neutrophils were found to release significant (P less than 0.05) amounts of the granular enzymes, but not of LDH in response to immunoglobulin G aggregates. There was no difference in the percent release exhibited by rheumatoid versus control neutrophils. Studies delineating the effects of rheumatoid factor sera and normal sera on aggregate-induced enzyme release revealed a significant negative correlation between the amount of rheumatoid factor in the sera and the percent release of beta-glucuronidase and lysozyme but not of LDH. These studies thus demonstrate no abnormalities in rheumatoid neutrophil or rheumatoid serum enzyme activities or in neutrophil response to immunoglobulin G aggregates. They suggest, however, that rheumatoid factor may partially inhibit the release of lysosomal enzymes, thus suppressing this important component of the rheumatoid inflammatory process.

Arthritis, Rheumatoid↗

Black stain and dental caries in schoolchildren in Potenza, Italy.

This study examined the correlation between dark pigmented dental plaque (black stain) and caries. Black stain was observed in 67 of 1086 schoolchildren (from 6-12 years old). The mean DMF-T was 0.49 = 1.05 for children with black stain and 0.97 = 1.40 for children with black without black stain (p<0.05). The results suggest an association between black stain and a decreased caries experience at least in the permanent dentition. Further studies are necessary to examine the etiology and whether or not black stain can protect against caries.

Child↗