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Biomedical subjects

J Schweiger

Publications and source records attributed to J Schweiger.

11 recordsLinked to original sources

Immediate postural responses to total nasal obstruction.

Twenty-five nasal breathing adults were radiographically examined before and after their nasal respiratory pattern had been artificially eliminated for a period of 1 hour. Six angular and six linear variables were measured to determine the extent of the postural reflexive behavior of the cranium, mandible, hyoid bone, tongue, and lips. All subjects coped in their own individual way with the environmental impact. The most generalized findings were parting of the lips (p < 0.05), a drop in mandibular position (p < 0.001), and a downward movement of the hyoid bone (p < 0.05). Cranial extension did not reach statistical significance (p = 0.06). The relevance of these findings relative to primate experiments and human clinical research is discussed. If the same postural reactions are maintained over a long-term period, they may be instrumental in influencing the vertical craniofacial growth pattern.

Adaptation, Physiological↗

Regioisomeric 5(3)-aminomethyl-3(5)-phenylisoxazoles: synthesis, spectroscopic discrimination, and muscarinic activity.

The regioselective synthesis of isomeric 5(3)-aminomethyl-3(5)-phenyl isoxazoles using different methods is described. Spectroscopic data, especially mass spectrometric fragmentation, were used to identify and characterize the regioisomers. The muscarinic activity of these isoxazoles was assayed on isolated guinea-pig ileum and atria as well as on isolated rabbit vas deferens.

Animals↗

Cyclosporine-associated central neurotoxicity after heart transplantation.

Cyclosporine central neurotoxicity has been described after bone marrow, kidney, and liver transplantation but has not been well documented after heart transplantation. This case illustrates severe reversible neurotoxicity after heart transplantation with characteristic radiographic changes in magnetic resonance imaging.

Brain↗

Denial in heart transplant candidates.

The concept of denial is important for the psychosomatic understanding of cardiovascular disease and treatment. This study evaluated denial using several psychometric assessment scales in patients referred for psychiatric evaluations prior to heart transplantation. Surviving patients who had a mean survival of more than 38 months had less denial than nonsurviving patients who had a mean survival of 4 months. These findings are very preliminary, but interesting, and would encourage further investigation of denial in these patients. Denial is a complex psychological variable, only part of which may be applicable to surgery patients.

Denial, Psychological↗

Physician-nurse collegiality in the medical school curriculum: exploratory workshop and student questionnaire.

Medical education is the key to improvements in physician-nurse relationships and communication. The results of a workshop for second-year medical students on collegiality organized by The Mount Sinai Hospital Department of Nursing and the Mount Sinai School of Medicine are presented. The workshop follow-up roundtable discussion is summarized and the results of a survey of medical students' perception of professional nursing are presented.

Adult↗

Role transition from graduate to staff nurse: a qualitative analysis.

The purpose of this study was to describe the initial steps in the role transition of graduate to staff nurse. During the first 3 weeks of an orientation to a clinical unit in an acute care hospital, graduate nurses and their preceptors used feedback sheets to document the learning activities of the graduate nurse, communicate the need for and evaluation of learning experiences, and plan activities to meet the continued needs of graduate nurses. Daily feedback sheets from 27 orientees and preceptors were analyzed using content analysis. A model representing the process and components of role transition was developed. The model was based on five themes which emerged from the data: Real Nurse Work, Guidance, Transitional Processes, Institutional Context, and Interpersonal Dynamics. Analysis of results revealed that the initial transition of a graduate nurse to the role of a staff nurse was a dynamic and interactive process occurring between the graduate nurse and the preceptor. Guided learning led to progress in balancing increasingly complex care within a specific institution. Interpersonal dynamics among staff, preceptors, and graduate nurses affected the process of role transition.

Adult↗

Patients who die awaiting heart transplantation.

In the United States, heart donor availability has increasingly failed to keep pace with rising demand. Transplant data were obtained from the United Network for Organ Sharing for 1988, 1989, and 1990 and by survey of 50 heart transplantation centers, which performed 1932 transplantations between 1983 and 1989. According to the United Network for Organ Sharing, 512 patients on the waiting list died in 1988; 527, in 1989; 650, in 1990, and if present trends continue more than 800 will have died in 1991. Similar numbers of patients were inactivated or removed from the list each year. Only 49% of patients (1647 of 3390) on the heart transplant waiting list at some time in 1988 underwent the procedure in that year. For 1989 the figure fell to 42% (1630 of 3915 patients). Survey data revealed a threefold increase in the ratio of the number of patients who died/number of patients who underwent transplantation from 0.07 in 1983 to 0.21 in 1989 and in the ratio (number of patients who died+number of patients who were removed from the list)/number of patients who underwent transplantation from 0.12 in 1983 to 0.38 in 1989. The major causes of death among waiting patients were congestive heart failure (46%) and arrhythmia (29%). From 1983 to 1989, 55% (134 of 243) of those patients with documented urgency status died in the intensive care unit; 45% (109 of 243) died elsewhere. Waiting time for patients dying in the intensive care unit rose from 10.7 days in 1985 to 50.3 days in 1989; patients dying out of the intensive care unit waited 103.7 days in 1985 and 85.6 days in 1989. In conclusion, the number and proportion of potential recipients who die awaiting heart transplantation is increasing every year. Congestive heart failure and arrhythmia are the major causes of death, and similar numbers of patients die in and out of the intensive care unit.

Adolescent↗