Biomedical subjects

J Selby

Publications and source records attributed to J Selby.

5 recordsLinked to original sources

PubMed1989

Genetic epidemiology of persistent islet cell antibodies among IDDM patients.

The persistence of cytoplasmic islet cell antibodies (ICA) more than a year after diagnosis of insulin-dependent diabetes mellitus (IDDM) was investigated in 43 families with at least two children with IDDM. The prevalence of persistent ICA among IDDM patients was 16%. Persistence of ICA appeared to be familial in that siblings with IDDM were significantly more concordant for the presence or for the absence of ICA than expected by chance (P = 0.04). Patients with persistent ICA were older on average at onset of IDDM than patients without persistent ICA after adjusting for duration of disease (P = 0.004). Persistence of ICA was not significantly associated with HLA DR type, immunoglobulin genotype, insulin allele class, sex, history of viral diseases, or prior vaccinations.

Autoantibodies↗

PubMed1988

Evaluating outcomes of pregnancy in diabetic women. Epidemiologic considerations and recommended indicators.

Many programs have been applied in various settings to reduce adverse outcomes of pregnancy in women with diabetes. Efforts to standardize criteria and methods for evaluating these programs are relatively recent. Without such standardization, evaluation of the impact of many programs and comparisons among programs have not been possible. We review the suitability of available data sources for monitoring adverse outcomes of pregnancy in women with diabetes in light of epidemiological considerations relevant to selection of indicators of program impact. This article is intended to be a resource to help evaluate in a standardized fashion the impact of programs at a regional, state, or local level. We conclude that primary data (information collected by programs themselves) collected in a standardized manner are necessary for evaluation of programs for diabetes in pregnancy. Secondary data sources alone are of limited value for monitoring outcomes because of underreporting of maternal diabetes, especially in the absence of identified complications. Ultimately, the ability to rigorously assess the impact of efforts to improve outcomes of diabetes in pregnancy may depend on the creation of comprehensive statewide systems to identify women of childbearing age who have diabetes.

Congenital Abnormalities↗

PubMed1988

Proud to care.

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Aged↗

PubMedDate not supplied

Physician attitudes toward office based non-pharmacological treatment of anxiety.

Despite evidence indicating the effectiveness of behavioral techniques in treating anxiety symptoms and disorders, treatment of anxiety in the medical setting has tended to be largely pharmacological. This research project investigates the attitudes of a sample of practicing physicians toward utilization within their practices of non-pharmacological approaches in the treatment of anxiety.

Anxiety Disorders↗

PubMedDate not supplied

Close encounters.

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Counseling↗