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Biomedical subjects

J Setka

Publications and source records attributed to J Setka.

At least 19 recordsLinked to original sources
PubMed1991

[Bronchopulmonary changes in patients with idiopathic intestinal inflammation].

The authors examined a total of 64 patients with idiopathic inflammatory bowel diseases, 33 patients with Crohn's disease and 31 patients with proctocolitis to assess the possible frequency of pulmonary complications. An impaired ventilation was recorded in 33% patients with Crohn's disease and 25% patients who proctocolitis, in both groups an obstructive ventilation disorder predominated. In four patients (12.5%) with Crohn's disease cytological examination of bronchoalveolar lavage revealed alveolitis. The authors draw attention to relatively frequent bronchopulmonary complications of non-specific inflammatory bowel disease which are usually clinically silent.

Adult↗
PubMed1986

[Epithelial tumors of the large intestine in short-term tissue culture (relation to biological behavior)].

Short term tissue cultures on space substrate were made from 13 samples of normal colonic mucosa and non-tumours colonic lesions as well as from 28 samples of epithelial colonic tumours. The growth and morphological features of cultivated tumours were mostly connected with their original histological structure and biological behaviour. Epithelial structures from adenoma and carcinoma survived longer than those from non-tumorous lesions. Epithelial cells from villous adenomas and from familiar polypous colonic adenomas showed increased proliferation on space substrate similar to the growth of carcinoma cells.

Adenoma↗
PubMed1986

Relation between high-frequency electrical impedance and malignity of two L cell sublines.

Two L cell sublines (L-As and LC3), differing in the ability to induce sarcomas in irradiated C3H mice, were grown on special gold electrodes interrupted in the middle by a 50 micron wide slot. Electrical impedance of the two sublines was compared at 100 kHz in a special measuring device connected with an apparatus used for impedance measurement in clinics. Significantly lower values of impedance characterized the LC3 cells, which induced more sarcomas in susceptibility hosts than the L-As cells. This result agrees with the findings in human tumors compared with corresponding normal tissue or benign growth, and stresses the importance of the cell population as such in impedance measurements.

Animals↗
PubMed1976

[The use of impedance measurements in the colon].

Biological changes in tissue also affect its biophysical and consequently its electrical properties. By the method here described, high-frequency current is caused to flow through the tissue under examination and the voltage decrease is measured. Measuring equipment of the author's own design has been developed for routine use of the method. The results of repeated measurements in the rectum of 323 subjects show that malignant tumor always cause lesser voltage decreases than do intact or inflamed tissues. The method has already been used during coloscopy in 40 patients. The results were in full agreement with biopsy findings.

Adult↗