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Biomedical subjects

J Shachor

Publications and source records attributed to J Shachor.

8 recordsLinked to original sources
PubMed1987

Bronchial response to methacholine in parents of asthmatic children.

Cumulative dose response curves to inhaled methacholine were established in 28 parents of asthmatic children, seven parents of healthy children, and four asthmatic patients. Bronchial sensitivity was defined as the dose of methacholine causing a 25 percent decrease in specific airway conductance while bronchial reactivity was determined by the slope of the cumulative dose response curve. Results indicated that parents with allergic rhinitis or airflow limitation in small airways may represent a high risk group, while parents with no atopy and normal pulmonary functions may reflect only the inherited characteristics of bronchial response.

Adolescent↗
PubMed1986

Long-term survival in bronchogenic carcinoma with a solitary metastasis.

Partial resection of a huge anaplastic large cell carcinoma of the upper lobe of the right lung was performed in a 47-year-old patient in order to relieve symptoms of pulmonary hypertrophic osteoarthropathy. Several months later a solitary metastasis was noted in the muscles of the right forearm. The metastasis was resected and the forearm irradiated. The patient was further treated with injections of autologous tumour cell vaccine and BCG. Today, 7 years later, the patient is alive, without any signs of neoplastic disease.

Carcinoma, Small Cell↗
PubMed1986

Changing pattern of lung tuberculosis.

In 46 (20%) of 233 consecutive patients with active lung tuberculosis, the localization of the tuberculous process was unusual. The majority of patients (81%) were greater than 40 years of age. Men predominated in the usual localized tuberculosis group, whereas women predominated in the group with unusual localized tuberculosis (UNLT). The most common site of tuberculosis in the UNLT group was the anterior segment of the upper lobe or the middle lobe. In 17.5% of the patients in the UNLT group, the diagnosis was established by thoracotomy only. In patients with "protracted pneumonia," or chest X-ray suggestive of neoplastic disease, tuberculosis should be included in the differential diagnosis, irrespective of the site of the lesion.

Adolescent↗
PubMed1978

The effect of sera from chronic lymphocytic leukemia patients on normal mitogen-stimulated lymphocytes. A possible correlation with the patients' T and B lymphocytes.

Serum from chronic lymphocytic leukemia (CLL) patients was examined for its effect on normal lymphocytes stimulated by phytohemagglutinin and pokeweed. Responses of the patients' lymphocytes were similarly examined. E and EAC rosettes were also tested. A significantly increased transformation response was found when normal lymphocytes were exposed to sera from those patients who had a reduced number of E-rosette-forming lymphocytes (mean 8%) as compared to the response to sera from patients with a higher number of E-rosette-forming cells. The results suggest that a factor is present in sera from some CLL patients which stimulates the transformation of mitogen-stimulated lymphocytes and which seems to be related to the number of the patient's T and B lymphocytes and perhaps with a T suppressor effect on B lymphocytes.

Aged↗
PubMedDate not supplied

Toxoplasmosis in a patient with common variable immunodeficiency.

We describe here a case of common variable immunodeficiency with depression of both humoral and cellular immunity, manifested primarily by chronic toxoplasmosis. The presence of a lymphoma as the underlying etiology of the immunodeficiency was excluded. The clinical, histological, and immunological interrelations between immunodeficiency, toxoplasmosis and lymphoma are discussed.

Antibody Formation↗