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Biomedical subjects

J Sienkiewicz

Publications and source records attributed to J Sienkiewicz.

11 recordsLinked to original sources
PubMed2001

Survival rate of preserved cultures contained in baker's vaccine.

The studies comprised the preparation and preservation, by the method of spray-drying, of baker's vaccine composed of lactic acid bacteria. The selection of particular strains was conducted taking into consideration the fermentation activity and growth dynamics of Lactobacillus rods isolated from plant material. Mixed vaccine was composed of chosen monocultures, characterized by the highest acidifying activity (4 strains). Before the vaccine was preserved, it had been used for making bread leaven (of rye flour) whose activity and usefulness for rye bread production was then determined The vaccine was subjected to spray-drying. The survival rate of Lactobacillus rods was determined directly after drying and during storage. It was found that the parameters of spray-drying applied in the experiment caused a considerable reduction in the number of vaccine components--by 2 log on average.

Colony Count, Microbial↗
PubMed1998

[Densitometric evaluation of mineral deposits in children and young people with food sensitivity who were treated by diet therapy].

Bone mineral content (BMC) and bone mineral density (BMD) of the whole skeleton were measured with dual energy x-ray absorptiometry (DEXA) using DPX-L bone densitometer (Lunar) in 240 caucasian subjects with food hypersensitivity, aged 2-18 years, fed milk-free diet (mean duration: 3.6 yrs). DEXA results were compared to the age and sex-matched reference population (n = 473) presenting normal consumption of milk and dairy products, Breast-feeding duration, social conditions and general physical activity did not differ in these groups. All subjects ranged between 3rd and 97th percentile for body weight and height and their nutritional status was similar in both groups, as assessed by means of anthropometric methods (BMI, skinfolds, midarm circumference). Mean values of total BMC and total BMD did not show significant differences between two groups of children, regarding to diet application. Although dietary calcium intake has a significant positive influence on the bone mineral content, our cross-sectional study suggests that the properly applied and controlled elimination diet should not disturb bone mass accumulation in children and adolescents with food allergy.

Adolescent↗
PubMed1992

[Acute encephalopathy in ethylene glycol poisoning].

Poisoning with ethylene glycol is the most frequent poisoning in our country. Acute encephalopathy during this poisoning may be a cause of important diagnostic difficulties, especially in the initial phase of the poisoning, due to the variety of symptoms and signs. Three cases of this poisoning are reported. All patients were erroneously referred and admitted to neurological hospital department. It is postulated that in each case of coma of unknown aetiology with signs suggesting damage to the brain stem and hyperventilation arterial blood gasometric examination should be done and blood and urine should be taken for toxicological investigations. In the treatment of glycol poisoning the most important task is to correct metabolic acidosis and to apply early dialysis treatment in serious intoxication.

Acidosis↗
PubMed1991

Psychotic complications of long-term levodopa treatment of Parkinson's disease.

The prevalence of psychotic complications of levodopa treatment was assessed in 198 Parkinson patients. The symptoms were seen in 44 (22.2%). Those who developed complications were significantly older at disease onset (63.3 +/- 9.2 vs 57.6 +/- 11.6). The observed psychiatric symptoms were classified into two categories: simple, including incidents of confusion alone or hallucinations with preserved insight, and complex, including delusions or chronic confusion without preserved insight. Patients with complex symptoms were significantly younger at the onset of the disease, and the duration of the disease prior to these psychiatric symptoms was longer than in the group of patients with simple symptomatology. Patients with complex symptoms were more susceptible to another central side-effect of the treatment: dyskinesias, than those with simple.

Adult↗
PubMed1988

[Incidence of simple goiter among the population of the Gołdap community].

The possibility of the occurrence of goiter endemia++ among the inhabitants of Gołdap community in the Suwałki voivodeship has been investigated. The investigations embraced 2488 persons, i.e. 21% of the population of the studied community. The occurrence of goiter was revealed in 38% of the investigated persons, and this observation lead to the conclusion that goiter is endemic among the population of the Gołdap community. Such features as high incidence of thyroid enlargement of low degree (OB and I), higher incidence of goiter in women than in men, absence of cases with hypothyroidism, and low incidence of nodular goiter, characterize the observed endemia++ as mild.

Adult↗
PubMedDate not supplied

[Central side effects of long-term treatment of Parkinson disease with levodopa preparations].

198 patients with Parkinson's disease on long-term treatment with L-dopa were evaluated for the presence of dyskinesias and psychiatric side-effects of the treatment. Dyskinesias were present in 53% of the patients. In a majority of them they appeared already during the first 2 years of the treatment. Younger patients seemed more susceptible to develop dyskinesias. Hallucinations, confusion, or delusions were observed in 22.2% of the patients. Older patients seemed more susceptible to develop these side-effects of the treatment. It seems that parkinsonian patients with later and earlier onset of the disease have different type of neuronal lesion responsible for the central side-effects of L-dopa.

Adult↗
PubMedDate not supplied

1-Haloacylpiperazines.

By direct acylation of piperazine with halogenocarboxylic acid chlorides in acid medium, the hydrochlorides of 1-haloacylpiperazines were obtained.

Acylation↗
PubMedDate not supplied

[Disorders of eye movements in degenerative diseases of the nervous system].

Eye movement disorders detected by oculography indicate abnormal function of specific brain areas involved in the motor control. Registration of conjugate eye movement can be very useful diagnostic tool to study neurodegenerative disorders of the brain. In some conditions oculographic registration may reveal eye movement abnormalities in subclinical stages of the disease.

Alzheimer Disease↗