PubMed Health⌕ Search

Biomedical subjects

J Sil

Publications and source records attributed to J Sil.

14 recordsLinked to original sources
PubMed1997

Antibiotic sensitivity patterns of actinomycetes isolated from patients of actinomycetoma.

The effectiveness of eight antibiotics against 30 human isolates of actinomycetoma agents belonging to 7 different species were tested by agar dilution and disc diffusion methods to evaluate the susceptibility patterns and to study drug resistance among the organisms. It was found that many of the isolates had developed partial or complete resistance to conventionally used antibiotics like cotrimoxazole, streptomycin and ampicillin, but almost all were sensitive to amikacin and ciprofloxacin. The two methods were equally effective for detecting sensitivity patterns of the Nocardia isolates.

Anti-Bacterial Agents↗
PubMed1980

Evaluation of the phenol-induced flagellar agglutination test for the identification of the cholera group of vibrios.

Applied routinely to 1081 recently isolated cultures, the phenol-induced slide-agglutination test (standard procedure) with flagellar antiserum corrently identified 98.9% of Vibrio cholerae strains of O type-I and NAG serotypes; 1.0% of cultures were unstable in phenol-saline. The incidence of instability and other types of defect was higher (7.3%) in older stock cultures. The majority of such strains were successfully tested by one of the three modified procedures. No cross-reactions were observed in 47 cultures of other species including the halophilic vibrios. Only one out of the 1205 cultures of V. cholerae tested by all procedures reacted negatively; this strain was found to lack functional flagella. These results establish the significance of flagellar specificity as a classificatory determinant in V. cholerae, and the fidelity and utility of the phenol test in routine bacteriology.

Agglutination Tests↗
PubMed1976

Effect of sulfadoxine on transmission of Vibrio cholerae infection among family contacts of cholera patients in Calcutta.

Sulfadoxine, a long-acting sulfonamide, and tetracycline were compared as regards their effectiveness in reducing transmission of cholera infection among the contacts of cholera patients in Calcutta. A total of 109 healthy family contacts of confirmed hospitalized cholera patients were treated with a single oral dose of sulfadoxine graded according to age. Another similar group of 101 contacts received 6 divided doses of oral tetracycline over a period of 3 days. All these contacts were bacteriologically examined for 15 days. Results showed that tetracycline was effective in significantly reducing the load of cholera infection from the 2nd to 6th day, while sulfadoxine was effective from the 3rd to the 6th day. The advantages and disadvantages of the two drugs as chemoprophylactic agents in cholera are discussed.

Administration, Oral↗