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J Slais

Publications and source records attributed to J Slais.

At least 19 recordsLinked to original sources
PubMed1992

Histochemistry of the racemose form of Cysticercus cellulosae.

The racemose form of brain cysticercosis arises from an intense proliferation of the bladder wall after the scolex part has degenerated. The proliferating zones are 2-3 times thicker than the remaining parts of the bladder and are characterized by a densely folded tegument and thick subtegumental and parenchymal layers. The tegument and subtegumental cells contain a large amount of acid mucosubstances with sulpho groups and hydrophilic lipids, and exhibit a high activity of alkaline and acid phosphatases. The parenchyma contains a large amount of glycogen. With the gradual aging of the bladder wall and with the first signs of autolysis, the enzymatic activity as well as the amounts of glycogen, neutral and acid mucosubstances, and proteins decrease, and the hydrophobic lipids prevail over the hydrophilic ones. The results obtained are important for the differential diagnostics of cestode larval stages in the human brain.

Animals↗
PubMed1982

Disseminated pulmonary adiaspiromycosis identified in bioptic material from the lung.

A disseminated form of pulmonary adiaspiromycosis was estimated in a 48 year old miner. The origin of a hypersensitivity mainly of an immediate allergic type became evident during an immunological examination and was partly indicated also by the tissue reaction and by elevated level of serum IgE (480 I.U.). Of great interest was the finding of a coagulation necrosis in the bioptic material. An examination of functions disclosed signs of a moderate obstruction which was latent when first observed with normal value of lung diffusion capacity. Its activation during stress was indicated by an increase in the value both of the residual volume and the IGV to the upper border of their limits. No apparent changes occurred in the disease during our two-year-investigation. Neither the total state of the patient nor the x-ray picture reflected the effect of a prolonged treatment with antituberculotics.

Antitubercular Agents↗
PubMed1981

Development of oncospheres of Taenia saginata after a concomitant infection by oral and subcutaneous routes.

Two experimental bulls (weight 200 kg each) were infected with activated oncospheres of Taenia saginata. The infective dose (160,000 oncospheres) was administered twice to each animal, once by oral, once by subcutaneous routes. At 6 hr p.i., a boil appeared at the site of puncture which attained a diameter of 5.5 cm and 6.2 cm respectively within 3 days, and a thickness of 1.8 cm and 2.2 cm. The postmortem disclosed an extremely weak total infestation of the muscles (approximately 30 cysticeri). The inflammatory tissue of subcutaneous foci contained eggs with an embryophore. Part of the eggs were enclosed in multinucleate giant cells. The tissue reaction differed in dependence on the viability of the oncosphere in the egg. Either giant cells were produced as in the presence of a foreign body, or there was a local accumulation of eosinophiles which after their destruction, were replaced by a crystalline conglomerate containing an egg in its centre. In addition, we found young stages of cysticerci affected by dystrophy. Remarkable eosinophile substances observed on the surface both of some eggs and of developing cysticerci (an analogy of the Splendone-Hoepli phenomenon) apparently indicated a binding of antibodies to the antigenic structure.

Animals↗
PubMed1980

Tissue reaction to spherical and lobular hydatid cysts of Echinococcus granulosus (Batsch, 1786).

We have studied the tissue reaction to spherical and lobular cysts of Echinococcus granulosus (Batsch, 1786) on a set of 108 observations of hydatidosis in the liver and lung of pigs. Typical of an early response of the host to a growing hydatid cyst is a local allergic inflammation characterized by a heavy infiltration of eosinophiles. If the infection is massive, sensitization increases the tissue reaction, and there is a marked exudation of eosinophiles into the pseudocyst which results in the ultimate death and liquidation of the parasite. In an organ infested with lobular and multilobular hydatid cysts, this early type of a tissue reaction persists around pouches in the hydatid wall. Typical of this reaction is an epitheloid rim, a new production of connective tissue, and an inflammatory infiltration. In fertile, large-sized cysts, the acute inflammatory reaction disappears from the inner side of the connective tissue sheath, and the wall of the hydatid remains in a direct contact with a thick layer of hyalinely degenerated, fibrous, connective tissue. A moderate, chronical, infiltrate along the periphery of the encapsulation provides evidence for a balanced relationship between the parasite and its host.

Animals↗
PubMed1976

Adiaspiromycosis in large free living carnivores.

Adiaspiromycosis was identified in 6 animals in the examination of the lungs of 90 large carnivores. Emmonsia crescens (Chrysosporium parvum var. crescens) was demonstrated as the causative agent in 5 cases of disease-in the badger (Meles meles), the otter (Lutra lutra) and the fox (Vulpes vulpes). E. parva was demonstrated in the remaining case of disease in a fox. The badger is a new, up to the present unknown host of E. crescens. The sporadic occurrence of adiaspiromycosis in the fox and the otter classifies this disease among rare diseases of this animals.

Animals↗
PubMed1976

Morphological determination of the age of Cysticercus bovis in very young calves with cysticercosis.

Characteristics and measurements are given for early developmental stages of Cysticercus bovis. The data emerging from our study indicate that the age of a one to two month-old larva from a spontaneous infection can reliably be determined in histological sections. On these grounds we have been able to determine that the cysticercus infection in the two calves (aged 21 and 27 days respectively) had been acquired prenatally.

Animals↗
PubMed1976

Histopathological changes and the genesis of adiaspiromycomas in mice infected intraperitoneally with Emmonsia cresens Emmons et Jellison, 1960.

Following an intraperitoneal inoculation with a suspension of aleuries of the funtus Emmonsia crescens, characteristic adiaspiromycomas originate in the abdominal cavity; a generalisation of the infection was caused by lymphogenic and haematogenic dissemination. At first, fragments of the mycelium became implanted and started to grow on the peritoneum; these were quickly destroyed by a gradually increasing leukocytic reaction. In the first month of infection nodules were formed mainly on predisposed sites in the abdominal cavity. Inside these nodules we found aleuries in the granulation tissue and a necrotic centre enclosing the accumulated inoculum. Development was delayed in aleuries released from agar particles after their resorption and in aleuries originating from remnants of the inoculum. This accounted for an initial heterogeneity of spherules in the nodules. The original nodules fus-d and formed large fibrous adiaspiromycomas. In the following months atypical spherules produced in large numbers by minute, developmentally retarded, budding spherules from the zone bordering the centres, were found inside these cel layer succumbed to regressive changes. The viability of these large spherules was confirmed by a finding of live adiaspores even at as late a time as 19 months after infection.

Animals↗
PubMed1975

Emmonsia parva as causal agent of adiaspiromycosis in a fox.

The authors report on adiaspiromycosis of a fox (Vulpes vulpes) caused by Emmonsia parva. Species diagnosis was made on the basis of dimensions of the fungus found in the lungs of the animal, the histopathological picture of tissue changes and the properties of the isolated culture. The identification of the fungus was also confirmed by experimental infection. The differential diagnosis of the agent of adiaspiromycosis is discussed by experimental infection. The differential diagnosed of the agent of adiaspiromycosis is discussed and attention is called to confusion of the species. E. crescens and E. parva in the past. The finding represents the first case of adiaspiromycosis due to E. parva in Europe.

Animals↗
PubMed1975

[Human taeniarhynchosis in the CSSR. Report given during the IVth symposium of the GDR on "Taeniarhynchosis-Cysticercosis" on April 26th, 1974 in Schwerin].

In the CSSR Taeniarhynchosis is not a notifiable disease. The details of frequency of occurrence of this disease are mainly based on investigations by the government medical laboratories, Prague. The number of persons infected with Taeniarhynchus saginatus increased in the last six years to 1700. Therefore this represents an increase of three times with carriers of tapeworm, as much compared with the results of previous years. The reason for this is not regarded as unsatisfactory veterinary observation by the government but the increase in consumption of raw beef.

Animals↗