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Biomedical subjects

J Small

Publications and source records attributed to J Small.

49 records · Page 3Linked to original sources
PubMed1980

Women general practitioners in Oxfordshire.

The proportion of women medical students is increasing as is the proportion of women trainees. However, we have found in a survey of general practices in Oxfordshire that women are still under-represented as general practitioner principals and that some women patients are seeking women doctors without success. We suggest that neither ability nor training is the problem and that there may be important difficulties for women arising from attitudes to women doctors and lack of opportunities for part-time work in general practice.

England↗
PubMed1980

Summit metabolism in newborn lambs.

Basal metabolic rate and then summit metabolic rate were measured using a water immersion technique in newborn lambs at 1 h or 4 h old. The mean rates of basal and summit metabolism were 51 +/- 1.5 and 235 +/- 7.9 w per m2 respectively. Summit metabolic rate was more closely related to body surface area than to body weight. Umbilical catheters were inserted at birth and blood samples were taken at 5 min of age and during the measurement of metabolic rate to examine changes in acid-base status and energy substrate concentrations. At birth varying degrees of metabolic acidosis and hyperlactaemia were observed. Summit metabolism was associated with the development of a further metabolic acidosis and with increases in the blood levels of lactate and excess lactate and the plasma levels of glucose, glycerol and free fatty acids. The relationships between summit metabolic rate, the metabolic state at birth and the change in metabolic state caused by cooling suggested that prepartum hypoxia was associated with a depression of the thermogenic response to cold stress and also with a depression of sympathetic nervous activity.

Acid-Base Equilibrium↗
PubMed1977

Some changes in the composition of maternal and fetal plasma from chronically catheterised sheep during short periods of reduced feed intake in late pregnancy.

Changes in the composition of maternal and fetal plasma from nine sheep were followed during periods of reduced feed intake lasting four to seven days. Feed rations were reduced between 120 and 128 days of gestation and this produced hypoglycaemia in mother and fetus. In each sheep there was a significant negative correlation between the glucose and corticosteroid concentrations in both maternal and fetal plasma, and there were positive correlations between the maternal and fetal plasma concentrations of glucose, and between the glucose and fructose concentrations of fetal plasma. Maternal and fetal packed cell volumes and the plasma concentrations of lactate and thyroxine remained relatively constant.

Adrenal Cortex Hormones↗
PubMed1976

Plasma thyroxine concentrations in ewes and their fetuses during the last six weeks of pregnancy.

Changes in plasma thyroxine (T4) concentrations were followed in 27 fetal sheep after surgical implantation of catheters. Fourteen days were required before stable concentrations of T4 were achieved, whether surgery was performed between 90 and 96 days or 109 and 120 days gestation. Twenty-three fetuses were followed to birth, and during the last four days the T4 concentrations showed no change in 11 fetuses and a significant decrease in the other 12. Birth occurred between 142 and 157 days gestation in both groups. There was a significant rise in T4 concentration during labour in all 23 fetuses. There were large differences among the plasma T4 concentrations of individual ewes which were not related to ambient temperature.

Animals↗
PubMedDate not supplied

Sparky.

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Aged↗