Biomedical subjects

J Sold-Darseff

Publications and source records attributed to J Sold-Darseff.

5 recordsLinked to original sources

PubMed2005

Filtering bleb function after clear cornea phacoemulsification: a prospective study.

AIM: To evaluate the influence of clear cornea phacoemulsification on filtering bleb morphology, function, and intraocular pressure (IOP) in glaucomatous eyes with previously successful filtering surgery. METHODS: The clinical course of 30 patients (30 eyes) who underwent clear cornea phacoemulsification after successful filtering glaucoma surgery was prospectively evaluated. Mean IOP and filtering bleb morphology (standardised assessment criteria and score 0-12, 12 = optimum) were determined before surgery, and 3 days, 6 months, and 12 months after surgery. The control group consisted of 36 patients with glaucoma after clear cornea phacoemulsification without previous filtering surgery. RESULTS: Mean IOP increased after phacoemulsification by about 2 mm Hg (preoperatively 14.28 (SD 3.71) mm Hg, 12 months postoperatively 16.33 (3.31) mm Hg, p = 0.006). 15 patients (50%) showed an IOP increase of >2 mm Hg, 11 patients (36.7%) had no IOP difference (within 2 mm Hg), and in four patients (13.3%) IOP decreased >2 mm Hg. Mean score of filtering bleb morphology 1 year after surgery decreased from 9.5 to 9.0 (p = 0.154). In three of 30 preoperatively IOP regulated eyes the postoperative IOP was 21 mm Hg. The control group showed an average IOP decrease of 2.01 mm Hg (p = 0.014) 12 months after cataract surgery. CONCLUSION: An increase in IOP was found 1 year after phacoemulsification in half of the filtered glaucomatous eyes. IOP in glaucomatous eyes without previous filtering surgery decreased in the same period. Cataract extraction using clear cornea phacoemulsification may be associated with a partial loss of the previously functioning filter and with an impairment of filtering bleb morphology.

Aged↗

PubMed2004

[Isolated Rosai-Dorfman disease].

A case of extranodal sinus histiocytosis with massive lymphadenopathy (ENSHML; Rosai-Dorfman disease) is reported. The patient presented with a history of intracranial tumour and exophthalmus. Clinical examination found a large mass in the left orbit and paranasal sinuses. Excisional biopsy showed a dense fibrous tissue with an infiltrate rich in macrophages. Further evaluation revealed a retroperitoneal mass with consecutive ureteral stenosis. Further histological and immunohistochemical investigation of the orbital mass, now in suspicion of a systemic disease showed an infiltrate of S-100-positive histiocytes and emperipolesis allowing the diagnosis of extranodal sinus histiocytosis. The correct histologic diagnosis was delayed due to the unusual and isolated extranodal localisation of the disease. The literature concerning extranodal manifestations of Rosai-Dorfman disease is reviewed. We suggest the additional evaluation of such rare and unusual cases in experienced reference centers.

Biopsy↗

PubMed1986

[Acupuncture for pain in the cranial region and for blepharospasm without organic cause].

In patients with functional ophthalmological disturbances classical acupuncture therapy was compared to a technique of inserting the needles close to superficial nerves. Seventy-five patients with migraine, 47 patients with functional blepharospasm, 18 with trigeminal neuralgia, and 9 with posttraumatic pain syndromes were treated. Treatment comprised seven sessions at four-day intervals. Of 62 patients undergoing classical acupuncture, 21 (33.9%) were subsequently free of complaints and 33 (53.2%) felt a great improvement. Nerve points were stimulated in 83 patients, 31 (38%) of whom were completely free of symptoms after treatment, and 45 of whom (54%) felt much better. Hence, there was no marked difference between the two methods as regards therapeutic effect. These results support the concept of acupuncture therapy being a combination of dermal stimulation and suggestion. The therapeutic approach to pain or blepharospasm by use of the mainly suggestive effects of acupuncture is recommended only if underlying organic diseases can be ruled out.

Acupuncture Therapy↗

PubMed1978

[Acupuncture in glaucoma (author's transl)].

Following the principles of classical Chinese acupuncture we treated 18 patients suffering from glaucoma chronicum simplex. We did not see any significant alterations of intraocular pressure whereas we attained improvement of recovery in some functional diseases such as blepharospasm or migraine. In our opinion therapeutic acupuncture works as a masked suggestive therapy. It is useless in organic diseases of the eye.

Acupuncture Therapy↗

PubMed1977

The intraocular pressure response of glaucomatous eyes to topically applied bupranolol. A pilot study.

Bupranolol 0.5% oily solution applied topically lowered intraocular pressure of glaucomatous eyes significantly. The pressure decrease is related to pretreatment pressure levels. The maximum effect occurred within 4 hours and lasted for more than 24 hours. No objective or subjective irritation could be attributed to the ophthalmic preparation. There was no significant effect on outflow facility, on blood pressure or tear flow. However, bupranolol produces local anesthesia on the eye. The problem of tachyphylaxis is discussed in the treatment of glaucoma with bupranolol eye drops.

Administration, Topical↗