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J Sorace

Publications and source records attributed to J Sorace.

3 recordsLinked to original sources
PubMed2000

Mapping XML documents into databases: a Data-Driven Framework for bioinformatic data interchange.

The Data-Driven Framework (DDF) described here addresses two major problems for healthcare Electronic Data Interchange, data formats and software development costs. The use of a standard XML Document Type Definition (DTD) allows robust representation in any application area and leverages industry-standard tools and development directions. The DDF allows reduced software development and maintenance costs since all data-entry and database tools are generated from the DTD. The DTD can change and the tools can be regenerated. The case-study below uses the DDF for reporting cell assays to determine the roles of factors influencing cellular gene expression and regulation.

Computer Communication Networks↗
PubMed1997

Functional bioinformatics: the cellular response database.

Biological Scientists function in an increasingly data rich environment. The emerging field of bioinformatics is attempting to insure that this flow of information can be structured to support the generation of significant biological hypothesis and ultimately new knowledge. To date, most of the current databases have focused on protein and nucleic acid sequence information as the principle type of data stored for further interpretation. In this paper, we describe the Cellular Response Database. This database stores functional information regarding the changes of cellular gene expression associated with various stimuli, and supports queries linking cell types, expressed genes, and inducers. The database is designed to support information-intensive queries to aid in the determination of biological function, and is flexible enough to allow the storage of a broad range of experimental data such as cytotoxicity data, immunoassays of target gene protein expression, and others.

Cell Physiological Phenomena↗