Apocrine hidrocystoma on the tip of a finger.
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Biomedical subjects
Publications and source records attributed to J Soto de Delás.
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Syringomas localized in the genital areas are unusual. There are only three cases reported describing syringomas on the penis. Owing to this atypical localization it is necessary to consider a differential diagnosis involving other papular lesions more frequent found on the penile skin.
We report a 69-year-old man with disseminated superficial actinic porokeratosis (DSAP) who developed a hyperkeratotic lesion on the distal third of the right forearm with the characteristic histopathological findings of squamous cell carcinoma and DSAP. A review of the literature revealed only four similar cases.
We present the case of a 64 year-old-male fur trader from Lerida (Spain), who consulted us because of a 2-week history of night fever and the presence of non-pruritic purpuric lesions on the distal third of the lower limbs. Laboratory findings demonstrated positive serology for brucellosis and cutaneous biopsy showed leukocytoclastic vasculitis. The pathogenesis of the cutaneous process is discussed. We also suggest that brucellosis should be included among the infections taken into account in patients suffering from leukocytoclastic vasculitis coming from brucella-endemic areas.
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The subepidermal calcified nodule (SNC), included under the idiopathic cutaneous calcifications, is an infrequent cutaneous process. We report a new case localized on the chin of an 18 month old child. We review the concept gathered from previous literature and we post the possible role which the mast cell may play in the genesis of the said deposits.
Subacute cutaneous lupus erythematosus (SCLE) is a recently described distinct subset of lupus erythematosus (LE) having characteristic clinical, serological and genetic features. The clinicopathological and serological findings of 5 patients are reported. From a clinical point of view, we describe two types of cutaneous lesions: psoriasiform and annular pattern. ANA were present in 80% of the cases, anti-Ro was present in 60%, and anti-La in 20%; anti-RNP was positive in 1 patient. Circulating immune complexes were detected in 2 patients, and low levels of complement factors (C3, C4) in another 2 patients. The B- cell alloantigens HLA-A2, HLA-Bw4 or HLA-DR3 were present in 60% of the cases. The cutaneous histopathology revealed important changes in the epidermis. Our findings are similar to those described by most other authors. Also, we would like to emphasize the low disease activity and benign course of our patients.
The clinical and pathological findings in five patients with dermatomyositis are described. The diagnostic value of the cutaneous lesions in the disease, indicating the histological patterns of each cutaneous sign is stressed. Based in our experience and in the reviewed literature, we consider that Gottron's papules and poikilodermatomyositis present histological aspects that allow us to confirm the diagnosis suspected by clinical findings. Likewise we review some special difficult aspects of the disease such as infantile forms, association with neoplasias and overlap syndromes.
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