Allergic contact dermatitis caused by colistin sulfate & bacitracin.
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Biomedical subjects
Publications and source records attributed to J Sowa.
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A patient with psoriasis was found to have a large skin tumor on his scrotum. He had received psoralen and ultraviolet A radiation therapy to control psoriasis. Histopathologic study revealed that the tumor was a well-differentiated squamous cell carcinoma. We present this rare case and suggest that the genitalia be shielded during ultraviolet therapy.
In the years 1986-1990 within Upper Silesia Region (Katowice Voivodeship) 1240 larynx cancer cases were diagnosed. Larynx cancer standardized incidence rates there are: 12,5 cases per 100 thousand on the whole area, maximal--28.6 and minimal--2.2 per 100 thousand, taking into consideration 93 administrative units (45 towns and 48 community councils). Larynx cancer incidence rates were dynamically increasing every year by 3%. There has not been attained geographic correlation between highest larynx cancer incidence level and highest ambient air pollution.
During a five period (1986-1990) in Katowice province (Upper Silesia) there were 6,140 cases of lung cancer in males and 1,039 females recorded. The standardized (according to age structure of the world population) incidence of lung cancer in both groups, in 93 administrative units (45 cities, 48 communities) significantly vary and are geographically unevenly distributed. The incidence in selected areas in males can be compared with values characterizing regions of the world with highest indices (> 95 per 100,000); whereas in females the incidence of lung cancer is much lower. The prognosis for lung cancer incidence in the Upper Silesia, according to the regression analysis is pessimistic.
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Alpha-1-antitrypsin level and serum trypsin inhibitory activity were measured in patients with viral hepatitis, chronic hepatitis and liver cirrhosis. The most pronounced discrepancy between these two parameters were observed in patients with liver cirrhosis: the increase of alpha-1-At level was not accompanied by adequate increase of trypsin inhibitory activity. Some mechanisms potentially responsible for this discrepancy are discussed.
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