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Biomedical subjects

J Spirková

Publications and source records attributed to J Spirková.

12 recordsLinked to original sources
PubMed2006

[Bilateral retinal vasculitis with arterial aneurysms].

The authors reported unusual and rare condition of bilateral retinal vasculitis primarily affecting the central retinal artery at the nerve head and its 4 main branches. The most striking feature was the presence of the diffuse vitreous cells, occlusion of branch retinal artery, segmental periarterial infiltration, arterial sheating, retinal arterial aneurysms, disc swelling, peripheral retinal non perfusion and their complications. During 13 year's observation and treatment one eye went blind 3 years after initial examination. Second eye started the same clinical course two years after beginning of the disease. To avoid similar devastating course of the disease we started systemic steroids and immunosuppressive therapy, followed by photocoagulation of nonperfused peripheral retina and vitreoretinal surgery. We achieved stabilization of the disease with decreased visual functions. Comprehensive systemic work-up was unrevealing, no clear etiology was identified and diagnosis of idiopathic retinal vasculitis was made.

Adult↗
PubMed2006

[Iris racemose vascular anomalies].

Authors present 7 rare iris racemose vascular anomalies that were discovered by biomicroscopy during routine ocular examination. The morphology, clinical features and iris circulation of these cases are documented by iris fluoroangiography. They also report common features, some specific details of arrangement and classification criteria. The iris vascular anomaly appears to be benign stationary condition that has none systemic and ocular associations.

Adult↗
PubMed2002

[Retinal and retinal pigment epithelium hamartoma].

Authors present four patients with combined hamartoma of the retina and retinal pigment epithelium who were observed for a period of 10 years. The significance of this entity lies primarily in its resemblance to malignant condition of the retina and choroid and in the vizual reduction. Clinical finding, diagnosis, natural history, histopathology, association with other diseases and therapy are discussed in this report as well.

Adult↗
PubMed2001

[Isolated and combined occlusion of the cilioretinal artery and the central retinal vein].

Cilioretinal artery occlusion is rare pathological condition because of infrequent occurrence of the cilioretinal artery in the human retina. It presents as an isolated entity, or as a combined cilioretinal artery--central retinal vascular, mostly venous occlusion. Authors present the course, angiographic features, prognosis, risk factors and final outcome of the isolated cilioretinal artery occlusion and combined cilioretinal artery--central retinal vein occlusion. Occlusion of the cilioretinal artery is believed to result from obstruction of the central retinal vein, as a primary process, in the case of combined cilioretinal artery--central retinal vein occlusion.

Adult↗
PubMed2001

[Retinal vascular complications in systemic lupus erythematosus].

An analysis of three women with retinal vaso-occlusive disease in systemic lupus erythematosus produced evidence for this most severe ophthalmic complication during the acute phase of the syndrome. Vaso-occlusive retinopathy appeared 5 years after the onset of systemic symptomatology in all of them. Association of central nervous system lupus and circulating anti-coagulants with increased occurrence of severe retinal vaso-occlusive disease are the subject of the present report. Unilateral extensive photocoagulation of two cases appeared to result in successful therapy of neovascular glaucoma after the central retinal artery occlusion in one patient. Lupus erythematosus is very serious systemic and ocular disease also in present time.

Adult↗
PubMed1993

[Tortuous retinal vessels].

The authors observed an occurrence of tortuosity of retinal vessels from the group of 5,000 investigations of an ocular fundus. Elimination of all local reasons or symptoms of general diseases, even in spite of the great possibility of modification of this feature, three characteristic types were found. In two of them the familiar and hereditary occurrence was proved.

Congenital Abnormalities↗
PubMed1993

[Abnormal vessels in the iris in angiographic imaging].

During the examination of 210 eyes with blue irises by fluorescein angiography a few unusual vascular formations of the course, filling and caliber were revealed. Authors have divided them into four groups by similar angiographic pictures. Possible capillary haemangioma in connection with syndrome Sturge-Weber from the third group and angioma racemosum from the fourth group of examined irises are considered to be abnormal vessels. It is possible to state diagnosis by fluorescein angiography in many cases even without histological examination and to follow the dynamics of their possible development.

Arteriovenous Malformations↗
PubMed1992

[Hamartomas of the optic disc and adjacent retina].

The authors discuss some formations on the optic disk and close neighbourhood resembling tumours. They originate from various cellular elements in that area and are described as hamartomas. A progressive growth was recorded only in vascular hamartomas after unsuccessful therapeutic intervention, the remainder were stationary during observation periods of various lengths.

Adolescent↗
PubMed1991

[Early stages of angiomatosis of the retina and optic nerve disk].

Based on 13 years observations of three generations of relatives with v. Hippel-Lindau's disease the authors focus attention on early stages of clinically detectable retinal angiomatosis. They supplement these findings by an angioma on the optic disc in one sporadic case. They consider the ophthalmological diagnosis of priority importance for the patients and risk relatives and recommend a concept of presymptomatic screening to detect other organ sites of the disease. Early detection and treatment of lesions on eyes and other organs improves the prognosis and reduces early mortality.

Angiomatosis↗
PubMed1990

[Differentiation and prognosis of colloidal retinal dystrophy].

The authors investigated in a prospective investigation 27 patients of different age groups for 5 to 12 years with symmetrical, bilateral non-hereditary retinal drusen. The examination was focused on assessment of different types of drusen, on evaluation of the development and incidence of risk factors leading to complications and loss of central vision. The latter include the part of the spectrum of pathological manifestations in higher age groups which are included in the category of senile macular degeneration.

Adult↗
PubMed1989

[Juxtafoveolar telangiectasia and its complications].

Juxta-foveolar telangiectasias were followed in 10 patients, when only in one patient the same clinical picture has been observed in both eyes. Decrease of the central vision was heavily deteriorated in nearly all patients, with only one exception. In some patients the glucose tolerance has been outside the normal limits, therefore authors suspect some etiologic connections between both diseases.

Adult↗