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Biomedical subjects

J Staiger

Publications and source records attributed to J Staiger.

28 records · Page 2Linked to original sources

[Echocardiography during ergometric exercise (author's transl)].

Radiological heart volume estimations and echocardiographic studies were performed on 30 male and 15 female middle distance athletes at rest, during supine ergometric exercise at 10 and 100 Watt and 1 minute after excerise. During exercise, there is an increase in cardiac output, in the small hearts of 6%, in the large hearts of 16%, due to a small enddiastolic increase and an associated decrease in the endsystolic left ventricular diameter. At rest and at 50 Watt, the cardiac output, corrected for body surface area, was practically the same for all volunteers, at 100 Watt the volunteers with the largest hearts had the highest cardiac output. This is interpreted as evidence for increased cardio-circulatory reserves. The contractility parameters at the various exercise grades varied dependant on heart size; when related to heart rate the variations were practically abolished. The results suggest that variations in the dynamics of small and large hearts are not primarily due to intrinsic factors but rather related to extrinsic factors such as sympathetic drive expressed by the changes in heart rate.

Adolescent↗

[Diagnosis of bacterial endocarditis involving three valves by echocardiography (author's transl)].

Endocarditis was suspected in a 66-year-old man who had enterococcal septicaemia. Thrombotic involvement of the mitral, aortic and tricuspid valves by the endocarditis was demonstrated by echocardiography, the diagnosis and localisation of the endocarditic deposits being confirmed at necropsy, the patient's condition making operative treatment impossible. The characteristic echocardiographic finding was of abnormal echos from the valves with largely normal valve movements. Atrial myxoma and artefacts had to be considered in the differential diagnosis.

Aged↗

[Percutaneous transluminal revascularization of lower-leg arteries].

In 19 of more than 130 patients treated with percutaneous transluminal angioplasty (PTA), obstructions of the distal popliteal artery and the lower leg arteries encouraged us to extend the treatment to this vascular region. Two weeks after PTA the arteries were patent in 16 of the 19 cases (84%). These results are comparable with those of vascular surgery, but are gained with less injury to the patient and a shorter hospitalization time.

Aged↗

[Echocaridographic measurements of left ventricle, heart volume, and maximal oxygen uptake (author's transl)].

Echocardiograms, radiological heart volume and datas by treadmill-exercis of 50 endurance athlets were studied. There was a highly significant correlation between radiological heart volume and left ventricular dimension as well as left ventricular volume including stroke volume. Other good relations were found between echocardiographic measurements and maximal oxygen uptake. These findings of left ventricular echocardiographic dimensions compared with heart volume and oxygen uptake support the value of this method and permit its use in the analysis of physiological and pathologic changes.

Adolescent↗

[Echocardiographic diagnosis of thrombotic deposits in acute endocarditis (author's transl)].

This report describes the echocardiographic features seen in 6 patients with valvular vegetations as documented by autopsy or surgery. 4 mitral, 3 aortic and 1 tricuspid valves were investigated using M-mode echoscan(n = 8). Characteristic findings observed were non-uniform thickening of the typical valve pattern in sytole and diastole without restriction of valve motion. In 7 cases the exact echocardiographic localization of valvular vegetation was confirmed in situ, whereas localization of vegetation in tricuspid valve disease was uncomplete.

Acute Disease↗

[Myocardial infarct with a normal coronary angiogram].

In this paper evidence is presented that in few patients with clear cut myocardial infarction as judged by physical signs, ECG and laboratory findings, the arteriography and morphology still may indicate healthy, unaffected coronary arteris. In those cases first of all the differential diagnosis has to include a silent myocarditis by whatever origin. This assumption may also be correct, if there are no or only few signs for this disease. Extensive diagnostic precedures should be performed under those circumstances.

Adult↗

Nuclear deoxyribonucleic acid content in congenital cardiac malformations.

Cytophotometric measurements of the DNA content of human heart muscle nuclei were performed on normal and congenitally malformed hearts of children. Congenital malformations of the heart lead to an early increase of the ploidy pattern as a sign of myocardial overload. This increase is significant. It starts, at the earliest, after the 3rd week of life. The degree of polyploidization of the muscle nuclei in malformed hearts is dependent on the type of overload. Pressure load produces a stronger shift to higher ploidy values than does volume load. The polyploidization is not dependent on either the heart weight at autopsy or the age of the child. It may be concluded that increasing functional requirement is the main cause of physiological and pathological polyploidization in hearts of children.

Age Factors↗