PubMed Health⌕ Search

Biomedical subjects

J Stary

Publications and source records attributed to J Stary.

24 records · Page 2Linked to original sources
PubMed1989

Correlations of clinical and laboratory data for prognosis in childhood acute lymphoblastic leukemia.

Correlation of 24 different clinical and laboratory measures was performed for a calculation of the prognosis in 65 children with newly diagnosed acute lymphoblastic leukemia (ALL). The hematologic as well as genetic parameters were studied at the time of diagnosis. It was shown that the initial blast count in peripheral blood is the most important risk factor for the prognosis of ALL. Cytogenetic, DNA cytometric, and pedigree data correlate with blast count and also seem to be very important determinants for ALL prognosis. The statistically significant increase in the incidence of neoplasms in ALL families is reported.

Child↗
PubMed1986

[Chlamydia trachomatis in patients with genital contact infections in Austria--studies of 3,367 patients].

In order to evaluate the epidemiological importance of Chlamydia trachomatis (C. trachomatis) as a genital microorganism, data were obtained from 3,367 patients with sexually transmitted diseases in Vienna and analyzed by computer-assisted methods. C. trachomatis was cultured in 26.1% of 2,594 patients investigated for the first time. The microorganism was found more often in male patients (31.3%) than in female patients (21%). 32.2% of positive Chlamydia cultures were obtained from patients with non-gonococcal urethritis (NGU) and 64% from postgonococcal urethritis (PGU) patients. A high coincidence with Neisseria gonorrhoeae (N. gonorrhoeae) was detected in males (31.2%) and females (43.5%). Data on Mycoplasma hominis (M. hominis), and Ureaplasma urealyticum (U. urealyticum) show that, in contrast to the low incidence of M. hominis and U. urealyticum in males, the organisms were found predominantly in females.

Adult↗
PubMed1984

Cerebral function in hyperthyroid patients. Psychopathology, psychometric variables, central arousal and time perception before and after thyreostatic therapy.

Psychopathology, psychometric variables, central arousal and time experience were studied in 30 hyperthyroid female outpatients. While these patients could be significantly discriminated in several of the above-described measures during the acute state of the disease, the intergroup differences disappeared after thyreostatic therapy. The thyroxine level was correlated with elevated beta-activity and the latter with variables of psychopathology and time experience. Hormonal dysbalance in hyperthyroidism is discussed as a biological substrate for neurophysiological changes which in turn causes deterioration in mood and behavior.

Adult↗
PubMedDate not supplied

History of pediatric hematology-oncology in the Czech Republic.

Specialized treatment for children with hematologic and oncologic diseases in the Czech Republic has a relatively short history. Dr. Josef Koutecky in 1964 was the first to organize the discipline of oncologic treatments and started a department that has since grown to include six other senior members. They treat over 250 new patients a year (approximately 150 malignant tumors) with an incidence similar to that in other European nations. Most are treated on cooperative group protocols with other centers in Europe and North America. Over 30 children also receive bone marrow transplants yearly from this group. Hematologic diseases including leukemia were first treated by D.r. O. Hrodek since the late 1950s in the Second Department of Pediatrics in Prague. Eight other centers in the Czech Republic besides Motol treat children with leukemia. Since 1985 they have followed the Berlin-Frankfurt-Münster (BFM) protocols for patients with acute lymphoblastic leukemia (ALL) and acute myeloblastic leukemia (AML). The Motol Hematology Section does about 20 transplants a year. New molecular biology laboratories in both sections aid the diagnosis and follow-up of the patients.

Child↗