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Biomedical subjects

J Staudt

Publications and source records attributed to J Staudt.

At least 19 recordsLinked to original sources
PubMed1995

Transcallosal removal of lesions affecting the third ventricle: an anatomic and clinical study.

A series of 54 patients with lesions affecting the third ventricle with a wide range of pathology were operated on by the transcallosal approach. Hydrocephalus was present in 68.5% of all patients, and preoperative shunting was performed in 73.0% of them. Before the partial callosotomy, 16 patients were studied by the use of a cognitive, affective, and behavioral battery, which was repeated 10 and 100 days after the operation. No physiological consequences were ever observed after the partial commissurotomy. The postoperative callosal defect was verified by magnetic resonance imaging. Furthermore, 40 formalin-fixed brains were sectioned to study the variations of the anterior cerebral arteries. On the other hand, magnetic resonance imaging measurements of the corpus callosum in 40 normal subjects were performed to establish a classification system for the corpus callosal area. The results showed a wide variability of the cross-sectional area of the corpus callosum. The differences in the thickness of the truncus were responsible for this variability; the length of the corpus callosum was uniform. This may suggest that subjects with a large corpus callosum may have more interhemispheric connections with higher specialization of each hemisphere and that a smaller number of callosal connections may correlate with more ipsilateral pathways and more independent hemispheres. The results and the clinical as well as anatomical material indicate that the anterior transcallosal route is a safe and feasible alternative in the management of a wide spectrum of pathological lesions within the third ventricle and deserves preference over the transcortical technique.

Adult↗
PubMed1991

[The surgical approach to the cochlear nucleus area].

The stimulation of the proximal auditory nerve or the Cochlear Nuclear Complex (CNC) situated in the lateral recess of the fourth ventricle is a possibility of hearing rehabilitation for patients suffering from bilateral deafness by bilateral cerebellopontine-angle tumors or by transsections of cochlear nerves on both sides. Using such anatomical landmarks as proximal cochlear nerve, flocculus, choroid plexus and taenia the surgeon can locate exactly the CNC for this stimulation. We investigated location, diameter and surrounding structures of the CNC on 10 human brains fixed in 10% formalin-solution and on 9 histological series of these subjects.

Acoustic Stimulation↗
PubMed1990

[Surgical anatomy of the petrous canal and posterior cranial fossa in relation to hearing preservation in surgery of acoustic neuroma].

The suboccipital (retrosigmoid) and the middle fossa routes are recommended for preservation of hearing in surgery for acoustic neuroma. We carried out a comparative study of the critical distances and bony landmarks on 520 petrous bones. Unlike the transtemporal route, the suboccipital approach offers no landmarks for identification of the common crus, the vestibule or the facial nerve; the lateral portion of the internal auditory canal is not always seen. The fundus can be seen in only 50% of bones without opening the labyrinth.

Adolescent↗
PubMed1989

[Comparative studies of the palatal mucosa under physiologic conditions and with removable dentures. I. Epithelial height and papillary bodies].

Epithelium changes caused by wearing of tissue-borne prosthesis were established on the basis of tissue specimens, taken away from the palate of 22 corpses with own teeth and 18 edentulous corpses with removable prosthesis. The epithelium height of the denture supporting area was reduced especially in the lateral and ventral cuts. The papillary body was significantly reduced.

Denture, Complete↗
PubMed1988

[A new method of coloring ground bone implants for light microscopy].

The material exploration for implants close in also histological study of bone-proofs after implantation in test animals. For light microscopical utilization of implant-bone-polishings was developed a new method of colouring what shows a better distinction between types of tissue around the implant and a time economizing of 3 h.

Animals↗
PubMed1988

[The problem of degradation and histocompatibility of bioactive ceramics in soft tissues. 2. Descriptive and morphometric evaluation of uncoated and coated bioactive ceramics].

After a 180 day lasting period of observation a persistent chronical inflammation occurred in the implants surrounding tissue of rats implanted with simple sintered biovitroceramics, where as the same material, coated with dental ceramic did not result in a comparable tissue reaction. After application of these coated implants we obtained a significant diminished formation of the periimplant connective tissue capsule. Inactivation of surfaces, being into contact with soft tissue, mentioned above, could be an economical, easy handling method.

Animals↗
PubMed1983

[Selected light microscopy and polarization optical studies of implant-bone interfaces].

Implant bone specimen of inert materials and of the material BVK Ap 40 mended histologically. The bone specimen were both decalcified and carried to the polish technique after plastics embedding. The experiments were carried out in miniature swines (type Mini-Lewe) and rabbits. Microscopical and polarisation optical investigations were carried out. A connective-tissue membrane was provable at the interface implant-bone in all cases with use of the biocompatible material titanium. With BVK Ap 40 was observed a direct compound with the bone.

Animals↗
PubMed1978

[The arterial blood supply of the human mandible].

The arteries of 22 mandibles injected with Kallocryl M were examined. The first group consisted of mandibles with the full complement of teeth. At the inner side, there were numerous anastomoses between the submental artery, the sublingual artery, the ascending palatine artery and the mylohyoid ramus. Furthermore, the dental rami branched into the periost. At the outside, the mental artery as well as the submental and inferior labial arteries contributed to the arterial supply. In the second group of mandibles (with intact incisors), these war a marked reduction of the anastomoses of the inferior alveolar artery in the middle region. The third group of mandibles (which were edentulous) showed anastomoses of the submental and sublingual arteries in the region of the incisors. The outside was supplied by the submental and inferior labial arteries. The mental artery exislar artery was demonstrated in 4 cases. The reduction of anastomoses concerned the inferior alveolar artery.

Aging↗
PubMed1977

Further evidence of teratogenic effects apparently produced by neurotransmitters during brain differentiation.

1. Adult male rats treated neonatally with the monoamine oxidase inhibitor pargyline showed significantly increased nuclear volumes of the nerve cells in the medial and central amygdaloid nuclei and significantly decreased concentrations of noradrenaline and dopamine in the hypothalamus as compared to control males. 2. Adult male rats treated neonatally with the monoamine depletor reserpine also displayed increased nuclear volumes of the nerve cells in the medial and central amygdaloid nuclei in comparison to the control males but significantly decreased nuclear volumes in comparison to the pargylinized males. Furthermore, the number of synapses in the stratum radiatum (CA 1-region) of the hippocampus was significantly decreased in the reserpinized males in comparison to the control males. 3. Adult male rats treated neonatally with the acetylcholine esterase inhibitor pyridostigmine showed a slight decrease of the noradrenaline concentration in the hypothalamus. These findings suggest that changes of neurotransmitter concentrations and/or turnover rates apparently produced by psychotrophic drugs during brain differentiation are able to exert teratogenic effects.

Amygdala↗