Acute calcific supraspinatus tendinitis in a three-year-old child.
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Biomedical subjects
Publications and source records attributed to J Stothard.
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The results of Kirschner wire and A.O. mini-screw fixation of fractures of the proximal phalanges and metacarpals in adults are compared with conservative treatment of displaced fractures and better results emerge from the use of A.O. screws than of Kirschner wires.
Arthrography of the first metacarpophalangeal joint at various times after trauma involving suspected rupture of the joint capsule or collateral ligaments has been performed since 1975 and the first four and a half years experience is reviewed. More variations in arthrogram appearance were found than previously reported and the appearance recorded elsewhere as being typical of a Stener lesion was not seen in the forty-one arthrograms examined. The selection of patients for surgery produced satisfactory results subjectively and objectively and the arthrographic appearance agreed with the operative findings up to twenty-one days after injury. Some patients were saved from unnecessary surgery by arthrography.
There has been good progress in inferring the evolutionary relationships within trypanosomes from DNA data as until relatively recently, many relationships have remained rather speculative. Ongoing molecular studies have provided data that have adequately shown Trypanosoma to be monophyletic and, rather surprisingly, that there are sharply contrasting levels of genetic variation within and between the major trypanosomatid groups. There are still, however, areas of research that could benefit from further development and resolution that broadly fall upon three questions. Are the current statements of evolutionary homology within ribosomal small sub-unit genes in need of refinement? Can the published phylograms be expanded upon to form 'supertrees' depicting further relationships? Does a bifurcating tree structure impose an untenable dogma upon trypanosomatid phylogeny where hybridisation or reticulate evolutionary steps have played a part? This article briefly addresses these three questions and, in so doing, hopes to stimulate further interest in the molecular evolution of the group.