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Biomedical subjects

J Ströder

Publications and source records attributed to J Ströder.

At least 55 records · Page 3Linked to original sources

[The unspecific reaction of inflammation in rickets due to lack of vitamin D (author's transl)].

10 children (3--18 months old) with Vit. D Deficiency Rickets were investigated by Rebuck skin windows for their ability to elicit unspecific inflammation before and after therapy. Differences to a control group (13 children) were statistically significant. In the acute phase of the disease beginning of inflammation is retarded, reduction of polymorphonuclear leucocytes in favour of mononuclear cells is less then in controls, the absolute quantity of exsudation is reduced too. After therapy inflammation is intensified and accelerated, but exsudation is still different from control children qualitatively and quantitatively. These findings add new facts to the data already known on impaired defence mechanisms in rickets.

Female↗

[Critical assessment of cortico-steroid therapy of acute thrombopenia (author's transl)].

Case histories of 75 children aged 6 months to 14 years were analysed, hospitalisation being for purpura due to thrombocytopenia. Sex distribution, age at first manifestation, frequency of infections immediately preceding purpura, frequency of chronic forms and letality coincide with previous literature reports. A favourable influence of corticosteroids on the acute phase of disease e.g. on purpura and disposition to haemorrhage, thrombocyte qualities, spleen- and liver enlargement as well as duration of hospitalisation was not realized.

Acute Disease↗

Localization of calcium-binding protein in intestinal tissue by immunofluorescence in normal, vitamin-D-deficient and uraemic subjects.

Antiserum directed against calcium-binding protein isolated from human kidneys was used for the immunofluorescent localization of calcium-binding protein in human intestine and kidney. Frozen sections of intestine obtained by biopsy from normal persons were tested by the indirect fluorescent antibody technique. Specific fluorescence indicating the presence of calciumbinding protein was observed at both the basal and apical poles of the intestinal absorptive cells while the goblet cells appeared to fluoresce non-specifically. Treatment of rachitic children with 25-hydroxycholecalciferol generally restored the pattern of fluorescence seen in intestinal tissue from normal persons. Examinations of intestinal biopsies from uraemic patients yielded variable results.

Adult↗