Biomedical subjects

J T Archie

Publications and source records attributed to J T Archie.

5 recordsLinked to original sources

PubMed1988

Uterine leiomyomas in the infertile patient: preoperative localization with MR imaging versus US and hysterosalpingography.

Eleven women with a history of infertility and uterine leiomyomas underwent magnetic resonance (MR) imaging of the pelvis prior to myomectomy. Nine also underwent preoperative pelvic ultrasonography (US), and ten underwent hysterosalpingography. All studies were interpreted prospectively by independent observers. With each imaging modality, the location (one of 11 anatomic segments), size, and appearance of detected uterine leiomyomas were determined and compared with surgical and histologic findings. Among the nine patients who underwent both MR and US, the sensitivity (85%) and accuracy (94%) of MR imaging for abnormal segments was significantly better than that of US (sensitivity = 69%, P = .015; accuracy = 87%, P = .043). For the ten patients who underwent both MR and hysterosalpingography, the sensitivity (91%) and accuracy (96%) of MR imaging was better than that of hysterosalpingography (sensitivity = 18%, P = .0005; accuracy = 72%, P = .0005). The specificities of the three modalities did not significantly differ (100%, 97%, and 98% for MR, US, and hysterosalpingography, respectively). These data suggest that MR imaging is superior to US or hysterosalpingography for preoperatively locating uterine leiomyomas.

Adult↗

PubMed1977

Transcervical tubal occlusion with a steerable hysteroscope: implantation of devices into extirpated human uteri.

A new steerable fiberoptic hysteroscope particularly useful in visualizing the tubal ostia has been evaluated in 61 extirpated uteri. The efficacy and safety of this hysteroscope were shown. The feasibility of deploying occlusive devices into the intramural portion of the tubes with the steerable hysteroscope was demonstrated. Whether these devices or modifications thereof will prove to be superior to other currently tested methods of occlusion, e.g., caustics, plastics, or cautery under in vivo conditions, remains to be established. The steerability of the hysteroscope has advantage irrespective of the method to achieve transcervical tubal occlusion as it allows coaxial alignment of the delivery.

Adult↗

PubMed1977

Hysteroscopy.

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Endoscopy↗

PubMed1975

Development of a steerable hysteroscope: studies in the baboon.

A steerable fiberoptic hysteroscope was developed with an integrated fluid circulatory system and a channel that can be used either for operative procedures or for the passage of a uterotubal occlusive device delivery assembly. The hysteroscope was demonstrated to be a safe and practical instrument for intrauterine observations, using the baboon as the animal model. Postpartum baboons were used for a majority of the experiments since the cervix of most cycling animals could not be sufficiently dilated to permit hysteroscope insertion. Estrogen-progesterone treatment resulted in softening of the cervix enough to allow hysteroscopic examination in 66 per cent of the animals so treated. Hysteroscopy was performed on 18 baboons. In almost all cases the uterotubal junctions were visualized and appeared as small slits or depressions. Measurements of the mean uterine length, fundal width, normal cervical diameter, and the diameter to which the cervix can maximally be dilated are reported for cycling, hormone-treated, and postpartum baboons.

Animals↗

PubMed1975

Adrenal and ovarian vein androgen levels and laparoscopic findings in hirsute women.

Hirsute women pose a diagnostic dilemma when urinary 17-ketosteroid and serum testosterone levels are normal. To locate the site of androgen excess in 19 hirsute women, blood samples were collested from the left ovarian and adrenal veins via a catheter insertedinto the right femoral vein. Laparoscopy and bilateral ovarian biopsies were also preformed in 18 of the 19 patients studied. Nine women had elevated 17ketosteroid (fivepatients) and/or antecubital serum testosterone (five patients) levels. Fourteen womanhad elevated testosterone concentrations distributed as follows: ovarian vein (six), adrenal vein (one), adrenal and ovarian veins (seven). Androstenedione was elevated in theovarian vein (seven) and both adrenal and ovarian veins (11) in 18 patients. Laparoscopic examinations revealed that less than 50 per cent of the enlarged ovaries could be detected by pelvic examination. Histologic studies suggested that these patients comprised two groups: a group (six patients) who appeared to ovulate and a group (12 patients) who lacked evidence of ovulation.

17-Hydroxycorticosteroids↗