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Biomedical subjects

J T Dietch

Publications and source records attributed to J T Dietch.

9 recordsLinked to original sources

The effect of nortriptyline in elderly patients with cardiac conduction disease.

Ten depressed, elderly patients with cardiac conduction abnormalities were given therapeutic doses of nortriptyline. Serial ECGs revealed no clinically significant adverse cardiac changes. These data, added to the findings of previous research, suggest that tricyclic antidepressants (TCAs) present little risk in patients with first degree atrioventricular block or hemiblock. Patients with bundle-branch block and bifascicular block are at greater risk of adverse cardiac sequelae but can be treated with TCAs. To maximize safety, the authors recommend monitoring serial ECGs and plasma TCA levels.

Aged↗

Aggressive dyscontrol in patients treated with benzodiazepines.

Periodic reports have suggested that benzodiazepines may be associated with a loss of control over aggressive impulses. Manifestations range from irritability to increased verbal hostility to frank assault. After reviewing data from case reports, experimental studies, and incidence reports, the authors attempt to characterize the phenomenon, estimate the incidence of clinically adverse sequelae to be less than 1%, and find consistent predictive indicators lacking.

Aggression↗

Depression in primary care: evolving concepts and approach to therapy.

Depression is one of the most commonly encountered maladies in clinical practice. Most depressed patients are seen first by nonpsychiatrist physicians who frequently overlook or ignore the depression. Many depressed patients can and should be treated by primary care physicians if those physicians are aware of diagnostic and management principles. These principles include knowledge of the clinically useful classifications, the wide variety of typical and atypical manifestations, the medical illnesses associated with depression, the neuroendocrinologic manifestations of major depression, and the use of aggressive, effective therapy. With those tools, the physician can effectively intervene in the course of an illness that affects a large portion of the population and causes considerable psychologic and physical anguish.

Antidepressive Agents, Tricyclic↗

Computerized tomographic scanning in cases of dementia.

In assessing the clinical value of computerized tomographic (CT) scanning in elderly patients with dementia, only one of 100 patients with dementia of insidious onset and no other abnormal neurologic signs was found to have a potentially treatable disorder. In a second group of 100 patients with dementia of abrupt onset or with additional abnormal neurologic signs, 12 were found to have a lesion that potentially required medical or surgical intervention. We conclude that a subgroup of patients with dementia, representing about a third of demented patients in our hospital, are unlikely to benefit from CT scanning.

Aged↗