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Biomedical subjects

J T Dowling

Publications and source records attributed to J T Dowling.

At least 19 recordsLinked to original sources

How to write a paper for publication.

Engaging in the scientific publication process can be for both altruistic and egotistical reasons; publication advances the state of scientific knowledge while advancing your institution and your career. Writing for publication means setting aside a location and time dedicated entirely to the process of planning and writing. It is easiest to begin with the Methods section, then the Results, followed by the Discussion, which is the most challenging part of a paper. A realistic assessment of the value of the article will determine the level of journal into which it is likely to gain acceptance. If your article is rejected by a journal, be consoled by the fact that 50% of articles that are initially rejected are eventually published. Following the steps outlined here can reduce the daunting task of writing to one of manageable proportions and can help overcome the mental block and procrastination that all of us have experienced when we set out to write a scientific paper.

Journal Article↗

Comparison of left and right ventricular function in acute myocardial infarction.

Pulmonary arterial end-diastolic and mean right atrial pressures were compared in 25 patients with acute myocardial infarction and in one patient with unstable angina. No consistent relationship was observed between these pressures. Simultaneous ventricular function curves relating the stroke work of each ventricle to its respective filling pressure were constructed on 34 occasions, dextran infusion or diuresis being used to alter the filling pressure. The curves from each ventricle were described mathematically by a quadratic (parabolic) function as well as by a straight line function and then compared by canonical correlation analysis. Alterations in the left ventricular function curves occurred with and without depression or right ventricular function curves. These hemodynamic measurements demonstrate that acute myocardial infarction can alter the relationship between left and right ventricular function.

Adult↗

Changes in heart dipole moment after surgical correction of atrial septal defect.

Spatial dipole moment of the heart (M) was measured in patients before and 1 to 2 weeks after repair of atrial septal defect. In normals three peaks of M were found, corresponding to excitation of the septum (M1), ventricular walls (M2), and basal portion of ventricles (M3). Most of the patients also had an M2a peak at 52 to 56 per cent of QRS duration. The patients with secundum defects were divided into two groups, A and B, depending on whether right ventricular pressure was less than or greater than 30 mm. Hg. M1 was smaller for the Group B patients than for the normals for Group A and decreased slightly after surgery. M2 was about half normal for Group A and one third normal for Group B. After surgery M2 increased for both Groups but was still below normal. There were small mean clockwise rotations of the M2 vector in the horizontal plane PO. The M2a vector pointed to the right anterior or posterior and generally downward. In three Group A patients the M2a peak disappeared PO but in two others it increased in magnitude with a counterclockwise rotation in the horizontal plane. In the Group B patients, M2a increased in all cases. The M3 vectors generally increased slightly in magnitude postoperatively. M3 pointed posteriorly in the normals but to the right in the patients, with little change in direction after surgery. Both P and T curves dropped in magnitude after surgery. The changes observed may be due in part to restoration of right ventricular blood volume towards normal after surgery. The remaining VCG abnormalities should be due to right ventricular hypertrophy.

Adolescent↗