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Biomedical subjects

J T Duncan

Publications and source records attributed to J T Duncan.

8 recordsLinked to original sources
PubMed1984

A clinical appraisal of flucloxacillin in the management of skin and soft tissue infections in Nigeria.

The resolution of skin and soft tissue infections following a single course of treatment with flucloxacillin was assessed in 235 patients recruited by nineteen physicians. In all, 88.5% of patients were completely cured or showed a highly satisfactory improvement after 3 to 12 days' treatment. Only three patients failed to show any improvement at all. Side-effects were limited to twelve patients (5.1%) all of whom were able to complete their course of treatment.

Abscess↗
PubMed1978

Fibrosarcoma of the scalp. Case report.

A parieto-occipital scalp tumor, noted in a Nigerian boy during the first month of his life, gradually increased in size, and after two attempts at partial removal there was a rapid increase in its size. When he was 17 years old, it measured 21 X 17 X 16 cm. There was no underlying skull defect. Complete excision of the tumor was achieved, and on histological examination it was found to be a fibrosarcoma. The patient was given a course of radiotherapy following wound healing. He remained well for 5 1/2 months but then had manifestations of small local recurrence and distant metastases that responded only minimally to another course of radiotherapy combined with cancer chemotherapy.

Adolescent↗
PubMed1977

Radiotherapy in the management of Kaposi's sarcoma in Nigeria.

Although Kaposi's sarcoma is now known to be far more common in the black African than was originally thought, it is rare in Nigeria. Facilities for radiotherapy are not available in areas of Africa where this condition occurs frequently. Various chemotherapeutic agents have been used either singly or in combination, with different results. In the locally confined lesions, it is believed that radiotherapy has an edge over the use of cytotoxic drugs. Five patients were seen and treated with radiation at the Lagos University Teaching Hospital in five years. They were all males, adults and came from the southern part of the country. All had histological confirmation of their disease as well as full investigations. Their histories are briefly reported. Response to chemotherapy from the literature has been discussed in order to highlight similar peculiarities attending the use of radiation on the normal tissues of the limbs. Ten different dose--time relationships were used on the five patients and these were plotted on double log scale. The results show that good response to curative radiotherapy varies inversely with the duration of the disease.

Adult↗