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Biomedical subjects

J T Mortensen

Publications and source records attributed to J T Mortensen.

32 records · Page 2Linked to original sources
PubMed1993

[The clientele at a clinic of occupational medicine--a medical statistical review].

To elucidate changes over time in the patient clientele examined at the department of occupational medicine, Aalborg Sygehus Nord, in the period 1982-1991, 4956 registrations related to referral and examination were studied in a retrospective investigation. The number of patients working at the time of examination has been steadily declining during the period. The number of patients with toxic encephalopathy is declining, while the number of patients with diseases in the musculoskeletal system is growing. Pregnant women with possible risk in the occupational environment and patients with cancers and mental illness form only a small part of the patient clientele in this department of occupational medicine. It is concluded that there have been changes in the patient clientele in the period 1982-1991. The small number of occupied patients diminishes the possibilities of replacement in work. Shorter periods of sickness and better possibilities for rehabilitation are expected to improve the situation in such a way, that the department of occupational medicine will be involved in health problems in the occupational environment in the future.

Adolescent↗
PubMed1993

[What did the consumers get out of the examination at a clinic of occupational medicine?].

In order to evaluate the function of a department of occupational medicine regarding consumer satisfaction, a mailed questionnaire was sent to 605 patients examined at the Department of Occupational Medicine, Aalborg Sygehus, during the period 01.10.1988-31.12.1989. A similar questionnaire was sent to the persons referring the patients to the department. Seventy-three percent of the patients and 76% of the persons referring patients participated in the investigation. Of the patients 44% had their expectations fulfilled, of the persons referring 78%. Half of the patients and 69% of the persons referring found the advice given relevant in relation to the health problem. Satisfaction among patients was related to whether the patients expected to start a compensation case or suffered from a chronic disease for which treatment was difficult. There was a difference between the expectations of the patients and persons referring the patients examination.

Denmark↗
PubMed1993

Toxicity of vitamin D analogues in rats fed diets with standard or low calcium contents.

Sprague-Dawley rats were fed either a standard diet with 0.9/0.7% Ca/P or a semisynthetic low-calcium diet with 0.5/0.4% Ca/P and treated orally for 28 days with 1 alpha-hydroxycholecalciferol [1 alpha (OH)D3], a synthetic analogue of the physiologically active form of vitamin D3, 1 alpha,25-dihydroxycholecalciferol [1 alpha,25(OH)2D3], at dose levels of 0.2 and 2.0 micrograms kg/day. The high dose caused severe hypercalcaemia with retarded growth, nephrosis, and structural bone changes in rats fed the standard diet. The same dose caused only slight hypercalcaemia without growth retardation or bone changes, and only minimally affected the kidneys in rats fed the low-calcium diet. Hypercalcaemia with less pronounced pathological changes was found in the standard diet low-dose rats, whereas no hypercalcemia or pathological changes were found in the low-calcium diet low-dose group. The rats fed the low-calcium diet tolerated 1 alpha(OH)D3 at dose levels up to 10 times higher than rats on the standard diet. The use of diets low in calcium and low in phosphorus will thus allow the administration of higher dosages of vitamin D compounds without causing hypercalcaemia. This may permit a better evaluation of the pharmacologic and toxic effects not directly associated with the calcium-regulating properties of vitamin D metabolites and analogues.

Animals↗
PubMed1992

The influence of halothane on spermatogenesis in surgical patients.

Seventeen male patients delivered a sperm sample before and 80-90 days after halothane anaesthesia, acting as their own control. The sample was tested according to WHO criteria. There was no difference before and after anaesthesia. We conclude that halothane used in normal anaesthetic concentration in combination with nitrous oxide during arthroscopic knee surgery had no certain effect on the quality of sperm.

Adult↗
PubMed1991

[Are health and disease equally distributed among children?].

Living conditions for children and young people are of great interest. In previous investigations, differences in sickness among social groups have been found. WHO plans to reduce differences in health conditions among groups within the countries by at least 25%. In this article, attention is drawn to inequalities in health among children in Denmark. Parameters such as the risk of stillbirth, congenital malformations and death during the first year of life do not differ between social groups. Where the less harsh data are concerned, inequalities still exist between social groups, also among Danish children. In relation to the goals set by WHO, it is important to be aware that the existing ways of measurement may not be sufficient.

Child↗
PubMed1991

[Social and health inequality in an area of community housing in Odense].

This investigation is a cross-sectional investigation based on the registers available which describe the conditions of health in children born in 1978 and resident in 1987 in two different social districts, one of which was socially, stressed while the other was slightly less stressed. The vaccination coverage was found to be lower in the socially stressed district and lower among immigrant children. More unvaccinated children were observed among children of mothers who received public assistance and of single parents. Hospital admissions on account of diagnoses due to infection were thrice as frequent from the socially stressed district. As regards height, weight and psychomotor status, no differences were observed between the districts. The investigation indicates that social inequalities cause health inequalities and that, in particular, there appears to be a need for health-promoting efforts where the socially stressed environments are concerned e.g. immigrant families.

Child↗
PubMed1989

[The work environment and male reproduction].

This review is focused on the connection between environmental factors in the workplace and male reproduction. Infertility is a problem for 10-15 per cent of Danish couples, and little is known about how large a part is played by environmental factors. It is now accepted that exposure by environmental hazards may result in partial or total infertility. The classic examples are exposure to lead, heat and radioactivity. Recent investigations have shown that occupational exposure to chemical substances such as dibromochloropropane and ethylene dibromide may interfere with spermiogenesis. In Denmark studies have been initiated concerning the connection between welding, lead and organic solvents, and the sperm-specimens. The findings of these studies support the hypothesis that, at levels currently accepted at workplaces, lead interferes especially with the sperm-cell concentration. In a few studies exposure to welding fumes have been found to have an adverse effect on sperm cell concentrations. All the investigations cited are marred by methodological problems. Despite these problems, it is internationally recognised that further studies are urgently needed, as are further epidemiological and methodological investigations in this field.

Environmental Exposure↗
PubMed1988

Risk for reduced sperm quality among metal workers, with special reference to welders.

The purpose of this study was to investigate whether men employed in the metal industry have sperm of poorer quality than men in other types of work. A postal questionnaire was sent to men employed in the metal industry, certain other types of nonmetal industries, and other types of employment in which the factors suspected to influence sperm quality were not present. By means of this questionnaire survey, it was hoped to define the possible influences of the work environment on sperm quality. Out of the total of 3,119 men included in the investigation, 2,517 (81%) filled out the questionnaire satisfactorily. Semen analysis was performed for all 3,119 men. There was a greater risk for poor sperm quality among welders than among men not employed in welding. The risk for poor sperm quality was increased for those welders who worked with stainless steel. Welding in general, and specifically with stainless steel, is connected with a risk of reduced sperm quality.

Adult↗
PubMed1986

Thiazides in the prophylactic treatment of recurrent idiopathic kidney stones.

In a double-blind prospective clinical study patients with at least two verified episodes of urolithiasis, but stone-free at the time of inclusion in the study, were subjected to prophylactic treatment with either bendroflumethiazide (2.5 mg) + 573 mg potassium chloride 3 times a day, or placebo. The material included a total of 22 patients, all males, aged 20-49 years. We found a clear tendency to reduced stone formation in the group treated with the active drug (P less than 0.01). Calcium excretion was reduced by 25-50% in 7 of 12 patients treated with thiazide.

Adult↗
PubMedDate not supplied

Dermatology life quality index: data from Danish inpatients and outpatients.

The aim of the present study was to provide data on the reliability and validity of a Danish translation of the Dermatology Life Quality Index (DLQI), a short measure of the impact of dermatological diseases on quality of life. The DLQI was administered to 200 outpatients and 100 hospitalized patients suffering from a range of dermatological diseases and to 100 sex- and age-matched healthy controls. Mean scores, internal consistency and test-retest reliability were comparable to the results reported for the original English version. Hospitalized patients reported greater impairment of disease-related quality of life than outpatients, and patients with atopic dermatitis and psoriasis exhibited greater scores than patients suffering from other dermatological diseases. Discriminant, construct and predictive validities of the Danish translation of the DLQI were satisfactory, as indicated by significant associations between DLQI scores and physician-rated disease severity, disease duration and the time patients were willing to spend each day on a hypothetical effective treatment. The results also suggest that the emphasis Danish patients place on various aspects of disability covered by the questionnaire is similar to that of English patients. In conclusion, the Danish translation of the DLQI showed satisfactory reliability and the preliminary results indicate that this version is a valid measure, which can be used in both research and clinical settings.

Adolescent↗