Biomedical subjects
Publications and source records attributed to J T Planten.
From the weight of the lenses of patients with senile cataract, ultrasonic measurements of the eyes of patients with acute diabetic refractive changes, and calculations on the basis of Legrand's theoretical eye, it appears that the conclusion can be drawn that these refractive changes are due to alterations in the refractive indices of the lens.
By weighing cataractous lenses and by scanning lenses of patients with acute diabetes with an ultrasonic A scan, it is made probable that hypermetropization in those cases is to be atributed to alterations of the refractive index of the lens.
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The increasing radius of the lens surfaces and the development of cortex and nucleus due to the differences in refractive indices, explain the physiological changes in refraction and accommodation which occur during life.
A 37-year-old man, who had an oat cell carcinoma of the left lung, lost in a few months a substantial part of both visual fields, on account of a destructive retinal process. This syndrome is known in the literature as a visual paraneoplastic syndrome, which clinically shows the very rapid development of a pseudoretinitis pigmentosa sine pigmento. For most of the patients described the visual problem was the presenting symptom. In contrast with most other described cases, our patient responded very well to systemic tumor treatment and his ocular process also came to a standstill after some delay. The nature of the relationship between the primary tumor and the photoreceptor destruction is not yet clear in detail. An auto-immune process probably forms the basis of the syndrome, but hormonal activity of the tumor could not be excluded in all cases.