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Biomedical subjects

J T Prior

Publications and source records attributed to J T Prior.

18 recordsLinked to original sources

Where have all the autopsies gone? A proposal for a centralized autopsy service.

A litany of reasons have been advanced to account for the decrease in hospital autopsy rates. Increased attention has recently been centered on the difficulty hospital and medical examiner morgues are encountering in controlling infectious disease and attempting to comply with federal and state environmental regulatory agencies. The problem has been highlighted by autopsy examinations upon increased numbers of immuno-compromised patients harboring both the HIV and secondary drug resistant tuberculosis organisms. These developments occur at a time when there are budgetary restraints on hospitals and medical examiners' offices facing large expenditures involving morgue reconstruction to comply with ventilatory and infection control procedures mandated by state and federal agencies. Challenging, also, are the liability aspects, as patients and staff are potentially exposed to a variety of infectious agents. A possible solution is presented involving central off-hospital site facilities to which hospital autopsies can be funneled. A community morgue meeting the strict standards of infection control would allow economy of scale from daily use with a full time support staff trained in the protocol of infectious disease control.

Autopsy↗

Variations in the delivery of medical care in central New York.

This paper presents an application of the Wennberg small area analysis methodology to the experience of a metropolitan county in upstate New York. It illustrates how these techniques can be used cooperatively by physicians and business to address purchaser concerns such as the impact of ambulatory surgery, the potential need for preadmission review and second opinion programs, and the contribution of high cost procedures to overall utilization and cost. The study found that use rates for most diagnoses and procedures were substantially below statewide norms, representing an annual savings of more than +30 million. It also found ambulatory surgery was effectively used as an alternative to hospitalization, and that high use rate areas involved high cost procedures targeted by second opinion and preadmission review programs.

Delivery of Health Care↗

Peutz-Jeghers syndrome. A clinicopathologic study of a large family with a 27-year follow-up.

A family group of ten patients with the Peutz-Jeghers syndrome has been followed for a 27-year period. Eight members of the family had one or more manifestations of the syndrome. One member of the family died following a bypass procedure of a nonresectable carcinoma of the jejunum. Postmortem examination revealed this to be an adenocarcinoma of the jejunum arising in a Peutz-Jeghers polyp and metastases were present in the mesenteric lymph nodes. Two members of the family developed breast carcinomas, one arising in a fibroadenoma; both patients died, one of metastatic breast carcinoma, the other of a second primary malignancy (adenocarcinoma of the jejunum arising in a Peutz-Jeghers polyp). Three family members had benign ovarian tumors, one patient had a benign breast tumor and another patient had a benign colloid thyroid nodule. While the authors of this report believe that they have added a documented case of an adenocarcinoma of the jejunum arising in a Peutz-Jeghers polyp to the literature, the exact risk of intestinal cancer in the Peutz-Jeghers syndrome is unknown, but probably very small. Gastrointestinal surgery should continue to be performed in symptomatic patients and all patients should be followed closely at regular intervals.

Adenocarcinoma↗