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Biomedical subjects

J T Rice

Publications and source records attributed to J T Rice.

4 recordsLinked to original sources
PubMed1979

Vaccination of chickens through the drinking water with a live, Pasteurella multocida, vaccine.

Broiler-type chickens were vaccinated orally at several ages with various dilutions of the Clemson University (CU) strain of Pasteurella multocida vaccine and then challenged orally with virulent strain P-1059 or strain X-73 of P. multocida to determine the degree of protection produced by vaccination. When vaccinated at 8 and 12 weeks of age for 2 consecutive days with a 1:133 dilution of the vaccine and then challenged at 17 and 19 weeks of age with strain X-73 and P-1059 P. multocida, respectively, no significant levels of protection were elicited in the vaccinates. Significant levels of protection were elicited in the vaccinates for 2 consecutive days at 9 weeks and at 13 weeks with 1:133 and 1:50 dilutions of the vaccine respectively, and then challenged at 16 weeks with strain X-73 and at 20 weeks with strain P-1059. Broilers vaccinated at 12 and 16 weeks for 3 consecutive days and then challenged at 20 weeks with strain X-73 showed a highly significant level of protection upon challenge when compared to the controls.

Administration, Oral↗
PubMed1978

Subcutaneous vaccination of chickens with a live, avirulent Pasteurella multocida, Vaccine.

The immunogenic responses to various routes of vaccination of broiler-type chickens to the Clemson University strain of Pasteurella multocida were evaluated. Broilers were vaccinated at 9 or 10 weeks of age using the oral (drinking water), palatine cleft, ocular, or subcutaneous injection routes. All birds were challenged at 11 or 12 weeks of age with virulent X-73 strain of P. multocida by the palatine cleft method. The degree of efficacy of the various vaccination routes differed among three experiments. Nevertheless, the subcutaneous route produced the greatest degree of protection in all experiments and in two experiments differences were highly significant (P less than .01). Protection levels as high as 95% and 97.5% were attained in broilers vaccinated subcutaneously and no undesirable lesions or cheesy masses formed under the skin in the back of the necks of broilers.

Administration, Oral↗