Biomedical subjects

J T Skeen

Publications and source records attributed to J T Skeen.

4 recordsLinked to original sources

PubMed1988

Ultrastructural heterogeneity in cerebral amyloid of Alzheimer's disease.

Cerebral amyloid deposits from five patients with presenile or senile cerebral disease of the Alzheimer type were stained with uranyl acetate and lead citrate or with periodic acid-thiocarbohydrazide-silver proteinate, and examined with traditional high-resolution electron microscopy and with a goniometer tilting stage. In addition to a carbohydrate-rich matrix, we also consistently found local cell-derived vesicles within plaque and dyshoric amyloid. The most likely source for these vesicles appeared to be degenerate neurites. Amyloid fibrils were intimately associated with plasmalemmata, particularly those of degenerate neurites, which supported a neuronal origin for the amyloid fibril of Alzheimer's disease.

Aged↗

PubMed1988

Intraoperative pulse oximetry in peripheral revascularization in an infant.

Vascular patency after reimplantation has been evaluated by numerous methods. A patient is described in whom pulse oximetry was used for this purpose. Other techniques of evaluating vascular patency are mentioned, and the physics of pulse oximetry are briefly discussed.

Amputation, Traumatic↗

PubMed1987

Varied uses of a thiopental infusion.

Explore the source record for details and available documents.

Adult↗

PubMed1976

Retention of learned temperature changes during problem solving.

In 2 studies (ns = 10, 9) college students were trained using biofeedback to lower or to raise finger temperature. Successful subjects were then asked to do distracting intellectual tasks, while simultaneously retaining the learned temperature changes. Results indicated that these changes could be maintained without detectable decreases in problem-solving efficiency in terms of either time or number of errors. These findings suggested that it might be possible for subjects to function efficiently outside the laboratory in their everyday activities while simultaneously exercising voluntary control over some autonomic processes.

Adult↗