Synchronous middle ear osteoma and adenoma.
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Adenoma↗
Biomedical subjects
J T Vrabec
Publications and source records attributed to J T Vrabec.
Promontory stimulation following translabyrinthine excision of acoustic neuroma with preservation of the cochlear nerve.
Promontory stimulation is an accurate method of assessing the functional integrity of the cochlear nerve by electrical stimulation. This technique is widely used in screening prospective candidates for cochlear implants. Recent reports have confirmed the integrity of cochlear nerve responses to electrical stimulation following labyrinthectomy and unsuccessful hearing preservation attempt by the retrosigmoid approach. In this report, the authors present three patients with intracanalicular acoustic neuromas excised through a translabyrinthine approach in which the cochlear nerve was preserved. In each patient, promontory stimulation elicited repeatable behavioral responses. These responses were consistent over a 9-month period of observation.
Auditory Threshold↗
Unilateral palatal adhesion for paralysis after high vagal injury.
Tumor involvement or sacrifice of the vagus nerve at the level of the jugular foramen is a cause of significant morbidity in skull base surgery. Management of the resulting dysphagia and dysphonia has been significantly improved by the development of vocal cord medialization. However, rehabilitation of palatal paralysis with the resulting velopharyngeal incompetence has not been widely addressed. In an effort to alleviate the symptoms of hypernasality and nasal reflux, unilateral adhesion of the palate to the posterior wall of the nasopharynx is proposed. This report summarizes the operative approach and results in eight patients. Results have been favourable with no significant postoperative complications observed to date.
Adult↗
Evaluation of basic fibroblast growth factor in tympanic membrane repair.
Basic fibroblast growth factor (bFGF) has been shown to enhance speed of wound repair at a number of anatomic sites. This study presents an evaluation of bFGF in a model of acute tympanic membrane (TM) perforation in order to assess rate of healing as well as structural and functional outcome. Perforations were created in the tympanic membranes of rats, then allowed to heal in the presence of topically applied bFGF with the opposite ear serving as a control. The growth factor was applied in repeated doses beginning 2 days after creation of the TM defect. The treated ears healed faster by an average of 4.0 days. The healed tympanic membranes were assessed using tympanometry and light microscopy. Structurally and functionally, the healed tympanic membranes were similar to the controls. The observed results indicate that bFGF promotes accelerated healing and restoration of normal architecture in acute TM defects.
Acoustic Impedance Tests↗
Suboccipital vestibular neurectomy: results and complications.
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Humans↗
Dermoid tumor of the middle ear: case report and literature review.
Dermoids and teratomas are frequently described in the head and neck, but are rarely found in the middle ear or temporal bone. We have recently managed a case of an extensive middle ear dermoid occurring in a 14-month-old female. The purpose of this article is to report the presentation and management of this case and to review the literature with respect to this entity.
Anti-Bacterial Agents↗
Management of bilateral acoustic neuroma.
This article has reviewed the genetic disorder, neurofibromatosis 2. The history, nomenclature, genetic etiology, epidemiology, diagnostic criteria, pathogenesis, and presentation of neurofibromatosis 2 have been given. A related but distinctly different disorder, neurofibromatosis 1, has also been described. The diagnostic evaluation of neurofibromatosis 2 has been discussed with an emphasis on the importance of early diagnosis. An analysis of the surgical treatment of bilateral acoustic neuromas as well as nonsurgical therapeutic alternatives has been presented. The results and complications in the operative management of 86 acoustic tumors in 49 patients with neurofibromatosis 2 have been described in detail. The poor immediate hearing results and the even poorer long-term hearing results have been examined in light of the invasive histopathology of these tumors. It has been emphasized that patients with neurofibromatosis 2 and asymptomatic family members require comprehensive, multidisciplined, long-term management.
Audiometry, Pure-Tone↗